Hypoplastic Left Heart Syndrome: Subendocardial Viability After Norwood Palliation

Hypoplastic Left Heart Syndrome: Subendocardial Viability After Norwood Palliation

This project has several objectives ranging from clinical data analysis to computational simulations as listed below:

1. Retrospective review of all patients with HLHS treated surgically and followed medically at the IRCCS Policlinico San Donato aiming to assess the SEVR after each step of Norwood palliation to analyze its influences on:

   • Mortality;
   • Occurrence of adverse events;
   • Outcome of the three-staged palliation;

2. Creation of a prospective registry that will enroll all patients surgically treated for HLHS at the IRCCS Policlinico San Donato.

Inclusion Criteria:

• Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato.

Exclusion Criteria:

• Patients with any type of atrioventricular discordance.
• Pediatric patients (age ≤18 years) with the diagnosis of hypoplastic left heart syndrome who underwent the Norwood palliation at the IRCCS Policlinico San Donato before March 2019.