Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis

Far Eastern Memorial Hospital

The aim of this study is to evaluate the efficacy between dienogest and danazol.

Objective: Women with adenomyosis or endometripsis are often suffered from dysmenorrhea or menorrhagia. Dienogest and danazol are frequently used for the treatment of endometriosis. However, there was no literature mentioned about which medication is better for the treatment of endometriosis. Thus, the aim of this study is to evaluate the efficacy between dienogest and danazol.

Methods: All consecutive women, who have endometriosis, will be randomized to receive dienogest or danazol treatment, and will assess symptoms severity, receive CA125 examination, sonographic examination at baseline, 4 weeks and 16 weeks after treatment.

Inclusion Criteria:

• > 20 years old
• Have an endometriosis-related condition (including adenomyosis, adenomyoma, ovarian endometrioma, or pelvic endometriosis).

Exclusion Criteria:

• Minors.
• Have a history of breast cancer or other cancers.
• Patients with vascular obstruction such as stroke.