Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Université de Sherbrooke | OTHER |
Not provided
Not provided
Not provided
This study aims to determine if preoperative EndoFlip measurement can effectively predict postoperative GERD-related quality of life and lower esophageal acid exposure.
Enrolled patients will be subjected to a pre-operative gastroscopy, 48-Hour Bravo pH study and EndoFlip. In addition, each patient will complete a GERD-related quality of life questionnaire (GERD-HRQL scale). One year after surgery, patients will undergo a follow up a gastroscopy, pH study, EndoFlip and the same quality of life questionnaire to predict the incidence of postoperative GERD and determine the effect of sleeve gastrectomy.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Before sleeve gastrectomy | No Intervention | Gastroesophageal Reflux Disease (GERD) will be evaluated before surgery. EndoFlip, gastroscopy, pH-study and GERD-Health-Related Quality of Life Questionnaire will be realized for all patients. | |
| Sleeve gastrectomy | Experimental | After the surgical intervention, new onset or worsening of GERD will be evaluated. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sleeve gastrectomy | Procedure | Patients will be recruited for a sleeve gastrectomy according to the guidelines of the National Institute of Health. |
|
| Measure | Description | Time Frame |
|---|---|---|
| New-onset of gastroesophageal reflux disease | total time of esophageal acid exposure (minutes) | 12 months postoperatively |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ringuette Vickie | Contact | 15147102044 | vickie.ringuette@usherbrooke.ca |
| Name | Affiliation | Role |
|---|---|---|
| François-Charles Malo | Université de Sherbrooke | Principal Investigator |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D005764 | Gastroesophageal Reflux |
| ID | Term |
|---|---|
| D015154 | Esophageal Motility Disorders |
| D003680 | Deglutition Disorders |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
Not provided
Not provided
Before/after study design
Not provided
Not provided
Not provided
Not provided
| D004066 | Digestive System Diseases |