Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness. China 's epidemic prevention and control has entered a new stage to restore the normal functioning of society and basic medical services, On Dec, 7, China released a circular on further optimizing its COVID-19 response, announcing 10 new prevention and control measures.This has marked the watershed for sharply increased number of elective surgical patients diagnosed with COVID-19 during preoperativley, fully recovered or during recovery.
Beijing faced a wave of omicron infection starting that would result in of a wide range of population infections. At which time there is limited evidence regarding the optimal timing of surgery following SARS-CoV-2 infection especially for omiron among Chinsese patients .This study intends to explore the relationship between the incidence of postoperative complications after elective surgery and COVID-19 infection in Peking Union Medical College Hospital, and provide data support for the policy formulation of elective surgical timing for patients after COVID-19 infection.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 0-1 week group | Patients who have been infected with Covid-19 with 0-1 week post-COVID interval before surgery. |
| |
| 1-2 weeks group | Patients who have been infected with Covid-19 with 1-2 weeks post-COVID interval before surgery. |
| |
| 2-3 weeks group | Patients who have been infected with Covid-19 with 2-3 weeks post-COVID interval before surgery. |
| |
| 3-4 weeks group | Patients who have been infected with Covid-19 with 3-4 weeks post-COVID interval before surgery. |
| |
| 4-5 weeks group | Patients who have been infected with Covid-19 with 4-5 weeks post-COVID interval before surgery. |
| |
| 5-6 weeks group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Receiving inpatient surgical intervention | Procedure | Receiving inpatient surgical intervention in Peking Union Medical College Hospital |
|
| Measure | Description | Time Frame |
|---|---|---|
| Perioperative complications | The composite primary outcome included pulmonary complications (pneumonia, acute respiratory distress syndrome, or acute respiratory failure, reintubation, unplanned use or prolongation of postoperative mechanical ventilation), cardiovascular complications (deep vein thrombosis, pulmonary embolism, myocardial infarction, newly onset arrhythmia, ischemic stroke, and acute kidney injury), and infectious complications other than pulmonary infection (urinary tract infection, surgical site infection, and sepsis). | During the procedure |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Length of hospital stay | Calculate the number of days the patient stays in the hospital. | Immediately after discharge |
| Readmission rate during 30 days after surgery | Readmission due to surgery complications during 30 days after operation |
Inclusion Criteria:
1. All patients having pre-operative SARS-CoV-2 infection diagnosis Dec 1st 2022 to Feb 28th 2023.
[The COVID-19 diagnosis is based on either (a) a positive RT-PCR nasopharyngeal swab, (b) positive antigen rest before surgery, or (c) clinical diagnosis made before surgery].
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
For the part of retrospective study，the investigators intend to include patients who had pre-operative SARS-CoV-2 infection diagnosis and received inpatient surgical intervention at Peking Union Medical College Hospital from December 1, 2022 to January 8, 2023.
For the part of prospective study，the investigators intend to include patients who will receive inpatient surgical intervention with pre-operative SARS-CoV-2 infection diagnosis at Peking Union Medical College Hospital from January 9, 2023 to February 28, 2023.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Shen Le, PhD | Peking Union Medical College Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking Union Medical College Hospital | Beijing | Beijing Municipality | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35194788 | Background | El-Boghdadly K, Cook TM, Goodacre T, Kua J, Denmark S, McNally S, Mercer N, Moonesinghe SR, Summerton DJ. Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update: A multidisciplinary consensus statement on behalf of the Association of Anaesthetists, Centre for Perioperative Care, Federation of Surgical Specialty Associations, Royal College of Anaesthetists, Royal College of Surgeons of England. Anaesthesia. 2022 May;77(5):580-587. doi: 10.1111/anae.15699. Epub 2022 Feb 22. | |
| 34793350 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Patients who have been infected with Covid-19 with 5-6 weeks post-COVID interval before surgery.
|
| over 6 weeks group | Patients who have been infected with Covid-19 with over 6 weeks post-COVID interval before surgery. |
|
| 30 days after operation |
| Postoperative mechanical ventilation time | Length of mechanical ventilation time after surgery | During the procedure |
| Mortality after operation | Mortality after operation in 1 month, 3 months, 6 months, 12 months | 1 month, 3 months, 6 months, 12 months after operation |
| Intraoperative respiratory complication | Intraoperative respiratory complication: a composite of intraoperative bronchospasm, poor oxygenation, and reintubation. | During the surgery |
| the WHODisability Assessment Schedule (WHODAS 2.0) |
| 6 months after operation |
| Brief Pain Inventory (BPI) | Brief Pain Inventory used to assess the intensity of pain | 6 months after operation |
| Background |
| COVIDSurg Collaborative. Outcomes and Their State-level Variation in Patients Undergoing Surgery With Perioperative SARS-CoV-2 Infection in the USA: A Prospective Multicenter Study. Ann Surg. 2022 Feb 1;275(2):247-251. doi: 10.1097/SLA.0000000000005310. |
| 36525270 | Background | Quinn KL, Huang A, Bell CM, Detsky AS, Lapointe-Shaw L, Rosella LC, Urbach DR, Razak F, Verma AA. Complications Following Elective Major Noncardiac Surgery Among Patients With Prior SARS-CoV-2 Infection. JAMA Netw Open. 2022 Dec 1;5(12):e2247341. doi: 10.1001/jamanetworkopen.2022.47341. |
| 36515945 | Background | Bryant JM, Boncyk CS, Rengel KF, Doan V, Snarskis C, McEvoy MD, McCarthy KY, Li G, Sandberg WS, Freundlich RE. Association of Time to Surgery After COVID-19 Infection With Risk of Postoperative Cardiovascular Morbidity. JAMA Netw Open. 2022 Dec 1;5(12):e2246922. doi: 10.1001/jamanetworkopen.2022.46922. |
| 38935110 | Derived | Che L, Yu J, Jin D, Bai X, Wang Y, Zhang Y, Xu L, Shen L, Huang Y. Impact of previous COVID-19 infection on postoperative complications and functional recovery: a 1-year follow-up ambispective cohort study. Int J Surg. 2025 Jan 1;111(1):481-491. doi: 10.1097/JS9.0000000000001869. |
| 37709339 | Derived | Che L, Yu J, Bai X, Wang Y, Zhang Y, Xu L, Shen L, Huang Y. Association between post-COVID-19 status and perioperative morbidity and mortality: protocol for an ambispective cohort study. BMJ Open. 2023 Sep 14;13(9):e074337. doi: 10.1136/bmjopen-2023-074337. |
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided