Needless Laser Injector for Antiaging Effect of Dermal Filler

Needless Laser Injector Versus Needle Injection for Antiaging Effect of Dermal Filler: A Randomized Split-face Comparison

The investigators aimed to evaluate the efficacy and safety of needless laser injector for antiaging effect of dermal filler.

A 24-week prospective, single-center, assessor-blinded, randomized, split-face study was conducted to compare the clinical efficacy and safety of needless laser injector versus needle injection for anti-aging effect of dermal filler.

Inclusion Criteria:

• patients who wanted to improve facial skin aging

Exclusion Criteria:

• a history of skin rejuvenation treatment (including filler, botulinum toxin, lasers, chemical peeling, and topical retinoid) within 6 month prior to the start of the study
• having a plan for skin rejuvenation treatment during the study
• current pregnancy or breastfeeding
• an allergy to polylactic acid (PLA) or hyaluronic acid (HA)
• uncontrolled medical diseases