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| Name | Class |
|---|---|
| The Danish Rheumatism Association | OTHER |
| Hvidovre University Hospital | OTHER |
| Bispebjerg Hospital | OTHER |
| Gentofte Hospital |
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The aim of this study is to investigate the incidence of intermetatarsal bursitis and Morton's neuroma in patients with metatarsalgia (i.e. pain in the forefoot) and control subjects by diagnostic imaging with ultrasound and MRI.
In a group of patients with intermetatarsal pain found by an orthopedic surgeon, the investigators want to assess the incidences of intermetatarsal bursitis and Morton's neuroma, using diagnostic imaging; ultrasound and MRI.
The hypothesis is, that intermetatarsal bursitis is an overlooked diagnosis in patients with metatarsalgia. As a result of sparse literature and lack of knowledge about this condition with symptoms mimicking Morton's neuroma, a part of patients diagnosed with Morton's neuroma, suffers from intermetatarsal bursitis instead.
Additionally, the investigators want to evaluate the clinical sign opening toes.
Based on clinical photos of the feet, the investigators want to document the presence of opening toes and investigate if there is a correlation with either intermetatarsal bursitis and/or Morton's neuroma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient group | Experimental | Patients with intermetatarsal pain have ultrasound and MRI done |
|
| Control group | Active Comparator | Healthy individuals (no forefoot pain) undergo ultrasound and MRI scan of the forefoot. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI with contrast | Diagnostic Test | MRI of the forefoot with contrast (Gadovist) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of intermetatarsal bursitis on MRI | High intensity on T2 weighted images, low signal on T1. Thin peripheral enhancement on T1 contrast enhanced pictures. | 8 weeks |
| Incidence of intermetatarsal bursitis on US | Hypoechoic mass between metatarsal heads closest to dorsal surface of foot. Compressible. Activity on power/color doppler. | 8 weeks |
| Incidence of Morton's neuroma on MRI | Low to Intermediate signal in T1 and T2. Contrast enhancement of the nodular focus. | 8 weeks |
| Incidence of Morton's neuroma on US | Hypoechoic mass between metatarsal heads closest to plantar surface of foot. Non-compressible. The interdigital nerve can be seen entering the mass. Close relation to the interdigital artery. | 8 weeks |
| Incidence of other pathology on MRI | Other pathology than intermetatarsal bursitis or Morton's neuroma. | 8 weeks |
| Incidence of other pathology on US | Other pathology than intermetatarsal bursitis or Morton's neuroma. | 8 weeks |
| Incidence of normal findings on MRI | When no findings is observed. | 8 weeks |
| Incidence of normal findings on US |
| Measure | Description | Time Frame |
|---|---|---|
| Opening toes | Presence of opening toes/V-sign/spreading toes. | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Radiology | Copenhagen | 2100 | Denmark |
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| ID | Term |
|---|---|
| D000070607 | Morton Neuroma |
| D037061 | Metatarsalgia |
| ID | Term |
|---|---|
| D005534 | Foot Diseases |
| D009140 | Musculoskeletal Diseases |
| D007592 | Joint Diseases |
| D009437 | Neuralgia |
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| ID | Term |
|---|---|
| D008279 | Magnetic Resonance Imaging |
| D014463 | Ultrasonography |
| ID | Term |
|---|---|
| D014054 | Tomography |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| OTHER |
This is a diagnostic study with a patient and a control group.
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| Ultrasound | Diagnostic Test | Ultrasound imaging of the forefoot |
|
When no findings is observed. |
| 8 weeks |
| D010523 |
| Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D009422 | Nervous System Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |