The aim of this study is to analyze the relationship between the blood biomarker GDF-15 and heart damage after stroke.

It is being conducted in France, in the Neurology Department of the Dijon University Hospital (Burgundy). The research is interventional because a biological blood test will be performed, as well as a heart rhythm recording and several cardiac echograms during the hospitalization of the participants and during the follow-up consultation scheduled 4 to 6 months after the stroke.

A total of 130 stroke patients will participate in this study.

Participation includes 4 visits:

• Inclusion visit (within 24 hours of the first stroke symptoms)
• visit 1 (within 24 to 72 hours of stroke)
• visit 2 (within 48 hours of visit 1)
• Visit 3 (approximately 4-6 months post-stroke)

Inclusion Criteria:

• Adult with acute symptomatic cerebral infarction documented by brain imaging on admission (cerebral angioscan or cerebral MRI)
• Whose first symptoms appeared within 24 hours before inclusion
• Whose consent to participate in this study was obtained from the patient or a close relative.

Exclusion Criteria:

• Person with a history of symptomatic stroke, either ischemic or hemorrhagic
• Anyone with a history of heart disease including: atrial fibrillation or flutter (known or discovered on admission), chronic heart failure, pacemaker, defibrillator, or other cardiac devices
• Person with acute heart failure, suspected infective endocarditis, STEMI, or concurrent pulmonary embolism
• A person who is not a member or beneficiary of a social security system
• Person deprived of liberty
• Person subject to a legal protection measure (curatorship, guardianship)
• Person subject to a legal protection measure
• Pregnant, parturient or breastfeeding woman