Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis

Adjunctive Use Of A Novel Hyaluronic Acid/Chlorhexidine Gel In The Non Surgical Treatment Of Periodontitis: A Split Mouth Randomized Controlled Trial

General Objective :

To evaluate the outcome of non surgical periodontal therapy with local drug delivery adjunct to scaling and root planning

Specific Objective :

To determine the effect of intra-pocket application of hyaluronic acid /chlorohexidine gel in non surgical periodontal treatment on clinical periodontal parameters and microbiological level .

Inclusion Criteria:

• Age : 20-60 years old
• At least 20 remaining teeth
• Periodontitis stage III and IV ,Grade A, B and C

Exclusion Criteria:

• Patients taking specific medications: antibiotic , anticoagulants or anti-inflammatory
• Previous periodontal therapy in the past 3-6 months.
• Immunocompromised patients
• Systemically diseased patients: Diabetes ,osteoporosis etc
• History of allergies or hypersensitivity reactions to chlorohexidine or Hyaluronic acid
• Pregnant or lactating women.
• Heavy Smokers (more than 20/day)