Effects and Mechanism of the Fully Immersive Virtual Reality Cognitive Training Based on Leisure Activities

Effects and Mechanism of the Fully Immersive Virtual Reality Cognitive Training Based on Leisure Activities: Cognitive, Daily Function, Quality of Life, Metabolic Biomarkers, and Electroencephalography

The aim of this study is to identify the effects of the immersive leisure-based VR cognitive training, and compare the intervention effects for elderly with MCI and SCD. The investigators anticipate the VR training can facilitate cognitive function, daily function, quality of life. The investigators anticipated the metabolic biomarkers, mechanism, and brain activities will be found. The significance of this study is identifying the effect of immersive leisure-based VR cognitive training, and confirming the metabolic biomarkers and brain activities. It could improve the accuracy of identification, prevent the progression to dementia, and lead the field of technological assistance to new opportunities for training.

Inclusion Criteria:

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MCI Inclusion Criteria:

age>=60 able to follow instruction MoCA<26 Scores on cognitive tests for individuals with MCI are 1 to 1.5 standard deviations below the mean for their age and education matched peers on culturally

SCD Inclusion Criteria:

age>=60 ECog-12 score >1 MoCA>=26; does not conform the standards of MCI and dementia

Exclusion Criteria:

- dizziness or epilepsy history; neurological or other orthopedic diseases with neurological or other orthopedic diseases unstable physical condition of VR cognitive training Recent psychiatric diagnosis, such as depression