Plaque Burden and Ischemia in MINOCA

Coronary Artery Plaque, Perivascular Inflammation and Myocardial Ischemia in Patients With Myocardial Infraction and Non-obstructive Coronary Arteries

The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery disease. The main question it aims to answer are:

• Identify coronary artery anatomy, plaque burden, composition and high-risk plaque features by CT coronary angiography in MINOCA
• Assess presence, extent and severity of myocardial ischemia in MINOCA

Participants will examined by CT coronary angiography and stress [12N] NH3 PET-MR.

Inclusion Criteria:

• Acute chest pain
• Elevated troponin
• Non-obstructive coronary arteries by coronary angiography

Exclusion Criteria:

• Obstructive coronary artery disease
• Contraindications against CT coronary angiography or stress [12N] NH3 PET-MR
• Not able to give informed consent