Comparative Study Between Safety and Effectiveness of High Versus Low Power HOLEP

Comparative Study Between Safety and Efficacy of High Versus Low Power HOLEP in Enucleation of the Prostate; Prospective Randomized Double Blind Trial

Holmium laser enucleation (HOLEP) has became a standard of treatment of large prostates that indicates surgery. HOLEP is widely used nowadays. Many settings are used but no optimal setting was world wide adopted. The aim of this trial is to assess the Low-power Holmium laser enucleation of the prostate (LP-HoLEP)and compare to high-power (HP-HoLEP) for enucleation efficiency pertaining to the advantages of lower cost and minimal postoperative dysuria, storage symptoms, and negative sexual impact.

Inclusion Criteria:

• large prostate indicated for surgical intervention.

Exclusion Criteria:

• prostate cancer
• recurrent adenomas
• associated neurologic factors that may affect outcomes (e.g., neurogenic bladder)