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| Name | Class |
|---|---|
| North Estonia Medical Centre | OTHER |
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Patients hospitalized with adhesive small bowel obstruction (SBO) are randomized to 2 study groups at admission after signing an informed consent form. Water-soluble contrast media (CM) will be administered after 4 or after 24 hours of nasogastric- tube decompression.
Patients presenting with symptoms of small bowel obstruction (SBO) will be evaluated and if the diagnosis of adhesive small bowel obstruction is made it must be decided what is the treatment of choice.
If immediate surgery is needed- it will not be delayed If patients are eligible for conservative management- they will be randomized to 2 study groups- contrast media (CM) after 4 hours of nasogastric-tube decompression and after 24 hours of nasogastric-tube decompression.
Contrast media challenge acquires radiographs (X-rays) to be taken after an interval (common practice) decided by the surgeon.
If at any point patient needs surgery- it will not be delayed. The results are compared. The hypothesis is, that if CM is administered sooner- it will help SBO resolution
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Contrast media 4 hours | Active Comparator | Patients will receive contrast media after 4 hours of nasogastric decompression |
|
| Contrast media 24 hours | Active Comparator | Patients will receive contrast media after 24 hours of nasogastric decompression |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Effect on contrast media depending on the time of its administratsion | Other | CM is a common practice when it comes to the management of small bowel obstruction. However there is no consensus as when it should be administered |
| Measure | Description | Time Frame |
|---|---|---|
| SBO resolution | SBO resolution with conservative measures
| Period of hospitalization- approximately 5 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Liis Jaanimäe, MD | Contact | +3725224012 | liis.jaanimae@kliinikum.ee | |
| Ceith Nikkolo, PhD | Contact | ceith.nikkolo@kliinikum.ee |
| Name | Affiliation | Role |
|---|---|---|
| Liis Jaanimäe | University of Tartu | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tartu University Hospital | Recruiting | Tartu | Tartu | 50406 | Estonia |
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Sealed envelope randomisation