Goal-directed Analgesia Using ANI During General Anesthesia in Children With Moyamoya Disease

Effect of Goal-directed Analgesia Using ANI (Analgesia/Nociception Index) During General Anesthesia in Children Undergoing EDAS (Encephaloduroarteriosynangiosis) Surgery for Moyamoya Disease: a Randomized Controlled Trial

Analgesia Nociception Index (ANI) has been proposed for the evaluation of the nociception-antinociception balance in the perioperative period. In pediatric patients with Moyamoay disease, where the management of analgesia may be rendered difficult by pharmacological changes, we hypothesised that the monitoring of analgesia with ANI would reduce intraoperative opioid consumption during EDAS surgery.

Inclusion Criteria:

• Pediatric patients receiving EDAS surgery for Moyamoya disease

Exclusion Criteria:

• ASA (American society of anesthsiologists classification) 4-5
• Emergency surgery
• patients with chronic pain on medication