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selective alpha-2 receptor agonists cause changes in intraocular pressure and pupillary size thus may affect patient quality of life.
In this research, we will analyze the effect of selective alpha-2 receptor agonists on the human eye and investigate ocular changes over 6 months after its topical use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glaucoma suspect group | Active Comparator | Cases diagnosed as glaucoma suspect |
|
| Post-refractive surgery group | Active Comparator | Cases had undergone refractive surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low dosage selective alpha-2 receptor agonists topical eyedrop | Drug | Using selective alpha-2 receptor agonists eyedrop in both groups with 0.2% concentration. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intraocular pressure | Changes in intraocular pressure measured in mmHg by applanation tonometry | Baseline and 6 months after regular use of the topical eyedrops |
| Measure | Description | Time Frame |
|---|---|---|
| Pupillary diameter | Changes in the pupillary diameter measured in mm by handheld pupillometer | Baseline and 6 months after regular use of the topical eyedrops |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Abdelshafy, MD | Contact | 01222328766 | ahmad4lg@gmail.com | |
| Marwa Abdelshafy, MD | Contact | 01008128810 | drmarwatabl2012@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed A Abdelshafy, MD | Benha University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ahmed Abdelshafy | Recruiting | Banhā | QA | 13511 | Egypt |
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| ID | Term |
|---|---|
| D009798 | Ocular Hypertension |
| D057108 | Corneal Wavefront Aberration |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
| D003316 | Corneal Diseases |
| D012030 | Refractive Errors |
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|
| High dosage selective alpha-2 receptor agonists topical eyedrop | Drug | Using selective alpha-2 receptor agonists eyedrop in both groups with 0.02% concentration. |
|
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