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| Name | Class |
|---|---|
| University of British Columbia | OTHER |
| Canadian Institutes of Health Research (CIHR) | OTHER_GOV |
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Pregnant people have a higher risk of severe COVID-19 disease. Pregnant people have been disproportionately impacted by COVID-19 infection control policies, which have resulted in higher rates of intimate partner violence, mental health distress, employment and income loss. This project examines the impact of accumulated individual health decisions, describing how perinatal healthcare use and outcomes changed during the COVID-19 pandemic.
Objectives, questions and hypotheses
This research study has two objectives:
Research questions and hypotheses have been operationalized according to our three themes:
Theme 1: Vaccination Theme 2: Perinatal Care Theme 3: Mental Health and Social Support
This project examines individual health decisions that occur within these structural environments, describing their accumulated impact on key pregnancy outcomes and care indicators related to three themes: vaccination, perinatal care, social supports and mental health. The decisions made during pregnancy have longitudinal impacts on the life of the pregnant person, future child, and family.(1) Given evidence of the particularly difficult situations faced by pregnant people, and the importance of these health decisions, it is important to understand how pandemic circumstances have shaped health decision-making. Understanding how and why pregnant people are making health decisions allows for better clinical and social support as the pandemic endures, and will inform future policy planning. This project is a cross-provincial, parallel mixed-methods study, with thematic data integration at the design and interpretation stages. Ontario and British Columbia were chosen as the two provinces of study because they both experienced a significant impact from COVID-19, both have access to comprehensive administrative health data, and a large number of live births each year.
This study was funded in late February 2022. The quantitative cohort creation plans and data access requests were finalized in late Fall 2022. Qualitative data collection was piloted in Summer 2022, data collection was complete in both provinces August 2023. Study completion is anticipated for February 2024.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-pandemic pregnancy and birth | Live hospital births that occurred Jan 1 - Mar 31 2019 | ||
| Pregnant and gave birth during the pandemic but before widespread COVID-19 vaccine availability | Live hospital births that occurred Jan 1 - Mar 31 2021 | ||
| Pregnant and gave birth during the pandemic and after widespread COVID-19 vaccine availability | Live hospital births that occurred Jan 1 - Mar 31 2022 |
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| Measure | Description | Time Frame |
|---|---|---|
| Vaccination | Were rates of Tdap vaccination different between 2019, 2021, and 2022 birth groups? Outcomes: Tdap (Ontario only) and COVID-19 vaccination rates | Specified groups from Jan 1 2019 to March 31 2022 (Tdap); Specified groups from Jan 1 2022 to March 31 2022 (Covid-19) |
| Perinatal Care | Were rates of in-person perinatal care different between 2019, 2021, and 2022 birth groups? Outcomes: Gestational diabetes screening, post-partum length of stay | Specified groups from Jan 1 2019 to March 31 2022 |
| Mental Health and Social Support | Were the rates of clinical diagnosis for new depression, anxiety, and adjustment disorders during pregnancy different between 2019, 2021, and 2022 birth groups? | Specified groups from Jan 1 2019 to March 31 2022 |
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Inclusion Criteria:
Exclusion Criteria:
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Our total population of Jan 1-Mar 31 births over the three-year study period is therefore approximately 105,000 in Ontario and 31,500 in British Columbia.
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| Name | Affiliation | Role |
|---|---|---|
| Meredith Vanstone, PhD | McMaster University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of British Columbia | Vancouver | British Columbia | V6T 1Z4 | Canada | ||
| McMaster University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34092185 | Background | Rockliffe L, Peters S, Heazell AEP, Smith DM. Factors influencing health behaviour change during pregnancy: a systematic review and meta-synthesis. Health Psychol Rev. 2021 Dec;15(4):613-632. doi: 10.1080/17437199.2021.1938632. Epub 2021 Jun 29. | |
| 37561748 | Background | Vanstone M, Correia RH, Howard M, Darling E, Bayrampour H, Carruthers A, Davis A, Hadid D, Hetherington E, Jones A, Kandasamy S, Kuyvenhoven C, Liauw J, McDonald SD, Mniszak C, Molinaro ML, Pahwa M, Patel T, Sadik M, Sanya N, Shen K, Greyson D. How do perceptions of Covid-19 risk impact pregnancy-related health decisions? A convergent parallel mixed-methods study protocol. PLoS One. 2023 Aug 10;18(8):e0288952. doi: 10.1371/journal.pone.0288952. eCollection 2023. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | May 6, 2025 | |
| Reset | May 21, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| May 6, 2025 | May 21, 2025 |
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| Hamilton |
| Ontario |
| L8P1H6 |
| Canada |
| 39560777 | Derived | Correia RH, Greyson D, Kirkwood D, Darling EK, Pahwa M, Bayrampour H, Jones A, Kuyvenhoven C, Liauw J, Vanstone M. New perinatal mental health conditions diagnosed during COVID-19: a population-based, retrospective cohort study of birthing people in Ontario. Arch Womens Ment Health. 2025 Aug;28(4):881-894. doi: 10.1007/s00737-024-01534-1. Epub 2024 Nov 19. |
| 39353631 | Derived | Greyson D, Correia R, Howard M, Darling EK, Kirkwood D, Davis A, Mniszak C, Jones A, Molinaro M, Vanstone M. SARS-CoV-2, Tdap, and influenza vaccination during pregnancy from 2019 to 2022 in Ontario, Canada: a population-based retrospective cohort study. CMAJ. 2024 Sep 30;196(32):E1100-E1113. doi: 10.1503/cmaj.231522. |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |