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To examine the effects of the general anesthesia method chosen in non-cardiac surgical operations of patients with cardiac risk on the levels of cardiac markers
To examine the effects of the general anesthesia method chosen in non-cardiac surgical operations of patients with cardiac risk on the levels of cardiac markers like; serum levels of the Creatine Kinase, Creatine Kinase Myocardial Band, high sensitive troponin, heart-type fatty acid-binding protein, ischemia-modified albumin and albumin. And evaluate the effect of anesthesia method on haemodynamic.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GROUP TIVA | Active Comparator | Anesthesia will be maintained with propofol (6-10 mg/kg/hour) and remifentanil (0.1-0.3 μg/kg/min). Blood will be taken from the patients at 0, 1 and 4 hours, centrifuged and stored at -80 degrees. From these examples, CK, CKMB, HIGH SENSITIVE TROPONIN, HFABP, IMA AND ALBUMIN will be studied. |
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| GROUP INHALATION ANESTHESIA | Active Comparator | Anesthesia will be maintained with sevoflurane (2 ml/min) 50% oxygen and remifentanil (0.1-0.3 μg/kg/min). Blood will be taken from the patients at 0, 1 and 4 hours, centrifuged and stored at -80 degrees. From these examples, CK, CKMB, HIGH SENSITIVE TROPONIN, HFABP, IMA AND ALBUMIN will be studied. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TIVA | Procedure | Anesthesia will be maintained with propofol (6-10 mg/kg/hour) and remifentanil (0.1-0.3 μg/kg/min). |
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| Measure | Description | Time Frame |
|---|---|---|
| comparing serum levels of ischemia modified albumin | serum levels of ischemia modified albumin (in terms of IU/ML) | intraoperative period |
| comparing serum levels of heart fatty acid binding protein | serum levels of heart fatty acid binding protein (in terms of mcg/L) | intraoperative period |
| Measure | Description | Time Frame |
|---|---|---|
| The effect of anesthesia method used in cardiac risk patients in terms of ephedrine consumption | used ephedrine amount (mg) | intraoperative period |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ayşenur Dostbil | Contact | +905333677796 | adostbil@hotmail.com | |
| Canan Atalay | Contact | +905333635318 | cananatalay@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Canan Atalat | Ataturk University | Study Director |
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| ID | Term |
|---|---|
| D000768 | Anesthesia, General |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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| GENERAL ANESTHESIA | Procedure | Anesthesia will be maintained with sevoflurane (2 ml/min) 50% oxygen and remifentanil (0.1-0.3 μg/kg/min). |
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