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The purpose of the study is to compare assessments of arm function following a standard exercise program in chronic stroke patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ARM-program | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Standard Occupational Therapy Arm Exercise Program | Other | Standard exercise program will be provided addressing shoulder, elbow, forearm, wrist, and hand with expectation that participant will complete 3 times a week. Exercise program will be updated at assessment timepoints as needed with change in arm function. |
| Measure | Description | Time Frame |
|---|---|---|
| change in arm impairment as assessed by Fugl Meyer - Upper Extremity assessment | This is a 33 item assessment and each is scored from 0 [unable to perform as instructed] - 2 [faultless performance] with a maximum score of 66. A higher number indicates better arm function. | Baseline, month 4, month 8, month 12, month 16, month 20, month 24 |
| Measure | Description | Time Frame |
|---|---|---|
| Change in integrity of corticospinal tract fibers as assessed by MRI with Diffusion Tensor Imaging (DTI). | Baseline, month 24 | |
| Change in motor evoked potential as assessed by Transcranial Magnetic Stimulation | Baseline, month 4, month 8, month 12, month 16, month 20, month 24 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sean Savitz, MD | UTHealth Houston | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | United States |
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|
| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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