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Evaluation of sun scoring system for predication of pancreatic fistula after Pancreaticoduodenectomy to facilitate timely intervention after Pancreaticoduodenectomy.
Pancreaticoduodenectomy is the only option curative intended in the treatment of resectable pancreatic ductal adenocarcinomas, duodenal carcinoma, ampullary carcinoma, lower common bile duct cholangiocarcinoma,. It is still associated with very high morbidity and mortality. [1]. Pancreatic cancer ranks as the seventh leading cause of cancer-related death worldwide, and the fourth among other cancers[2,3]. Pancreatic fistula(PF) is one of the most important complications after Pancreaticoduodenectomy, with an incidence of about 10% to 28%.[4].There are multiple risk factors for the predication of development of pancreatic fistula after pancreaticoduodenectomy which include soft gland texture, non-pancreatic cancer non-chronic pancreatitis pathology, small pancreatic duct diameter (<3 mm), and high intraoperative blood loss (>1000 mL) , excess intraoperative fluid administration and increased pancreatic parenchymal remnant volume [5,6,7]. Other reported risk factors as increased body mass index (BMI), poor preoperative nutrition, and male gender which preoperative may lead to pancreatic fistula [8.9]. Recent studies are deficient in evaluation and predication of pancreatic fistula . So the interest of our study to evaluate and predicate the risk factors and management of pancreatic fistula after Pancreaticoduodenectomy .
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| Measure | Description | Time Frame |
|---|---|---|
| predication of pancreatic fistula after Pancreaticoduodenectomy to facilitate timely intervention after Pancreaticoduodenectomy | Early prediction of pancreatic fistula post PD facilities threraputic intervention and life saving in some cases | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Reduce the morbidity and mortality and improve the quality after pancraticoduodenectomy | Management of pancreatic fistula post PD improve quality of life | Baseline |
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Inclusion Criteria:
All the cases indicated for Pancreaticoduedenectomy with :
Exclusion Criteria:
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All patients admitted to Assuit university hospitals which candidate for pancreaticoduodenectomy at the time of the study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mahmoud Saber Mekhemer, Resident | Contact | 01141608732 | mahmoud.saber.3291@gmail.com | |
| Salah Ibrahim Mohamad, MD | Contact | 01061616104 | salah.Ibrahim@med.au.edu.eg |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31210716 | Background | Li Y, Zhou F, Zhu DM, Zhang ZX, Yang J, Yao J, Wei YJ, Xu YL, Li DC, Zhou J. Novel risk scoring system for prediction of pancreatic fistula after pancreaticoduodenectomy. World J Gastroenterol. 2019 Jun 7;25(21):2650-2664. doi: 10.3748/wjg.v25.i21.2650. | |
| 26019457 | Background | Chen JY, Feng J, Wang XQ, Cai SW, Dong JH, Chen YL. Risk scoring system and predictor for clinically relevant pancreatic fistula after pancreaticoduodenectomy. World J Gastroenterol. 2015 May 21;21(19):5926-33. doi: 10.3748/wjg.v21.i19.5926. |
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| 30113999 | Background | Xia W, Zhou Y, Lin Y, Yu M, Yin Z, Lu X, Hou B, Jian Z. A Predictive Risk Scoring System for Clinically Relevant Pancreatic Fistula After Pancreaticoduodenectomy. Med Sci Monit. 2018 Aug 16;24:5719-5728. doi: 10.12659/MSM.911499. |