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The goal of this observational study is to learn about in STEMI with Primary PCI Patients. The main questions it aims to answer are:
Radiographic images of STEMI receiving primary PCI treatment in several chest pain centers in China will be included. The last image of the infarct-related vessel will be used as a target to calculate its AMR. The relationship between AMR and long-term clinical prognosis was analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| diagnostic cohort/derivation cohort | The diagnostic/derivation cohort included STEMI patients who underwent PCI within 12 hours and CMR. The optimal AMR cutoff value for diagnosing CMD using CMR was determined by analyzing ROC curves. | ||
| prognostic cohort/validation cohort | The prognostic cohort enrolled STEMI patients who underwent PPCI within 12 hours. All patients were followed up for at least 1 year. |
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| Measure | Description | Time Frame |
|---|---|---|
| MACEs | cardiac death, hospitalization for heart failure, target vessel revascularization，non-fatal MI | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| cardiac death | All cause deaths will be considered cardiac unless a definite noncardiac cause can be established. | 12 months |
| hospitalization for heart failure | Hospitalization for heart failure was defined as admission because of new or deteriorating signs and symptoms of heart failure combined with the findings of noninvasive imaging or elevated B-type natriuretic peptide(BNP) and/or N-terminal pro-BNP concentration, and a discharge diagnosis of congestive heart failure. |
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Inclusion Criteria:
Exclusion Criteria:
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All patients who underwent PPCI due to STEMI in several chest pain centers in China from January 1, 2012 to October 1, 2022
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| Name | Affiliation | Role |
|---|---|---|
| Muwei Li, MD | Fuwai central China cardiovascular hospotial | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shangqiu first people's Hospital | Shangqiu | Henan | 476000 | China | ||
| Department of Cardiology, First Affiliated Hospital of Xinxiang Medical University |
The personal information of a large number of patients is involved. IPD is not provided to protect the privacy of participants.
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| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D000072657 | ST Elevation Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| 12 months |
| target lesion revascularization | The following 3 conditions need to be met at the same time:
| 12 months |
| Repeated myocardial infarction | Repeated myocardial infarction | 12 months |
| Xinxiang |
| Henan |
| China |
| Yongcheng Central Hospital | Yongcheng | Henan | China |
| Fuwai central China cardiovascular Hospital | Zhengzhou | Henan | China |
| Renji Hospital, School of Medicine, Shanghai Jiao Tong University, | Shanghai | Shanghai Municipality | China |
| D009203 |
| Myocardial Infarction |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |