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| Name | Class |
|---|---|
| Alberta Cancer Foundation | OTHER |
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The purpose of this study is to implement a prehabilitation intervention to enhance recovery for people undergoing allogeneic stem cell transplant for hematologic malignancies. All participants in this study will receive a prehabilation intervention in addition to usual care (no change to their chemotherapy protocols or transplant) and several quality of life and fitness scores will be measured throughout the intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Prehabilitation | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Prehabilitation | Other | A multiphasic exercise prehabilitation program for alloHSCT candidates across each treatment phase, that includes behaviour change support |
|
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility of Implementing an Exercise Program for Patients Undergoing Allogeneic-HSCT, Measured by Participant Attendance | Review participant attendance/participation in the program and the questionnaires. | 6-9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Amount of Physical Activity Measured With Activity Tracker | Quantity of physical activity, measured in hours. | 6-9 months |
| Exercise Behaviour Measured with Modified Godin Leisure Time Exercise Questionnaire |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sarah Perry, MD, MSc | Contact | 403 944 9602 | 3 | sarah.perry2@ahs.ca |
| Chad Wagoner, PhD | Contact | 403-210-8482 | chad.wagoner@ucalgary.ca |
| Name | Affiliation | Role |
|---|---|---|
| Nicole Culos-Reed, PhD | Health and Wellness Lab and the Thrive Centre | Study Director |
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| ID | Term |
|---|---|
| D007938 | Leukemia |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| ID | Term |
|---|---|
| D000082622 | Preoperative Exercise |
| ID | Term |
|---|---|
| D019990 | Perioperative Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D013514 | Surgical Procedures, Operative |
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Hybrid implementation-effectiveness study
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Self reported measure of physical activity. Higher scores are better.
| 6-9 months |
| Patient Quality of Life Measured with the Functional Assessment of Cancer Therapy-Bone Marrow Transplant and EuroQol 5 Dimension 5 Level Questionnaire | Self reported physical, emotional and functional well-being. | 6-9 months |
| Level of Fatigue Measured with the Functional Assessment of Chronic Illness Therapy Fatigue Scale (FACIT-F) Questionnaire | Self reported level of fatigue during daily activities. Lower scores mean less fatigue. | 6-9 months |
| Amount of Anxiety and depression Measured with the Hospital Anxiety and Depression Scale (HADS) Questionnaire | Self reported level of anxiety and depression. Higher scores indicate more anxiety and depression. | 6-9 months |
| Amount of Symptom burden Measured with the Edmonton Symptom Assessment System-revised (ESAS-r) Questionnaire | Self reported symptoms. Higher scores indicate more symptoms. | 6-9 months |
| Patient's Performance Status Measured by the Eastern Cooperative Oncology Group (ECOG) Scale | Objective score of patient's level of functioning. Lower scores indicate better functioning. | 6-9 months |
| Handgrip Strength Measured by Handgrip Dynamometry | Maximum isometric strength of the hand and forearm muscles. | 6-9 months |
| Balance Measured by Single Leg Stance Test | Static postural and balance control, measured in seconds. | 6-9 months |
| Lower Limb Muscular Endurance Measured with 30-second sit-to-stand Test | Tests leg strength and endurance, measured in number of stands in 30 seconds. | 6-9 months |
| D001519 | Behavior |
| D015444 |
| Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |