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| Name | Class |
|---|---|
| University Paris 8 Vincennes Saint Denis | OTHER |
| ARSEP foundation | UNKNOWN |
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Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future (i.e., future thinking) .
While our previous work has shown that people with relapsing-remitting multiple sclerosis (pwRRMS) have autobiographical memory and future thought disorders, their impact on personal identity has not yet been explored. Based on a cognitive and clinical neuropsychology approach, this research project aims to better understand the cognitive mechanisms involved in the relationship between identity, autobiographical memory and future thinking in pwRRMS. We will examine the extent to which pwRRMS manage to maintain and reshape their identity through life experiences, with a particular interest in the potential integration of the disease as a facet of their identity. In addition, we will explore the positive and/or negative consequences of disease-related identity changes on emotional well-being and quality of life, as well as their links with the duration and severity of the disease. Overall, this research project will contribute to identify new therapeutic levers that can be used for the development of adapted and personalized care.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Clinical group | 45 individuals with relapsing-remitting multiple sclerosis |
| |
| Control group | 45 individuals with no chronic disease, matched in age, gender and level of education |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Neuropsychological tests and psychological questionnaires | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| Relationships between personal identity, autobiographical memory and future thinking | Scores obtained at the I AM and I WILL BE tasks assessing the access, qualitative properties of self-concepts, episodic richness and temporal organization of past and future events around self-concepts (between-group comparisons, pwRRMS versus control group) | 15 days |
| Measure | Description | Time Frame |
|---|---|---|
| Relationships between personal identity, psychological functioning and clinical characteristics | Correlations between IAM and I WILL BE scores and scores obtained at the different questionnaires (BRIEF COPE, Connor Davidson Resilience Scale, Satisfaction with Life Scale, Hospital Anxiety and Depression Scale) Correlations between IAM and I WILL BE scores and level of functional disability (Expanded Disability Status Scale) Correlations between IAM and I WILL BE scores and disease duration |
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For the clinical group:
Inclusion Criteria:
Non-inclusion Criteria:
For the control group:
Inclusion Criteria:
Non-inclusion Criteria:
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Primary care clinic
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alexandra Ernst, PhD | Contact | +33628496210 | aernst@univ-paris8.fr |
| Name | Affiliation | Role |
|---|---|---|
| Alexandra ERNST, PhD | Laboratoire DysCo - Université Paris 8 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital Raymond Poincaré Garches | Recruiting | Garches | Hauts De Seine | 92380 | France |
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|
| 15 days |
| ID | Term |
|---|---|
| D020529 | Multiple Sclerosis, Relapsing-Remitting |
| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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| ID | Term |
|---|---|
| D009483 | Neuropsychological Tests |
| ID | Term |
|---|---|
| D011581 | Psychological Tests |
| D004191 | Behavioral Disciplines and Activities |
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