Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction

Impact of Focused Low-intensity Shockwave Therapy (LiSWT) in Penile Disorders (Peyronie's Disease, Erectile Dysfunction, or Both), With or Without Intralesional Clostridial Collagenase (Xiaflex) Injection, Compared With Radial Shock Wave Therapy or Xiaflex Therapy

The purpose of this research is to determine the pure or additional effects of penile shockwave therapy with low intensity linear shock wave machine for penile curvature (and/or erectile dysfunction) vs patients' undergoing other treatments (including Xiaflex therapy, patients that have undergone older generations of SWT, or medical treatment).

Inclusion Criteria:

• Peyronie's Disease (PD) at any stage
• The presence of penile plaque or pain at erection or curvature
• PD therapy with or without simultaneous intralesional Xiaflex injection.

Exclusion Criteria:

• Prior penile surgery or LiSWT.
• Erective Dysfunction (ED) not responding to phosphodiesterase-type five inhibitors or intracavernosal injections.
• Unwillingness or inability to provide informed consent.
• Having active or life-threatening coagulopathies ore using anti-coagulation /anti-platelet medications