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| ID | Type | Description | Link |
|---|---|---|---|
| R00AG065457 | U.S. NIH Grant/Contract | View source | |
| K99AG065457 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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Assess the impact of a remote, app-delivered digital meditation intervention on emotional well-being of lonely older adults. Neuroimaging, electrophysiological (EEG), and autonomic physiology will be used to assess the neural correlates of the intervention. EEG and autonomic physiology will be collected while participants watch 30 min of an awe-inspiring movie. fMRI and autonomic physiology will be collected in the context of a social exploration/exploitation task.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| intervention | Experimental | Participants will engage with the digital meditation app delivering the intervention 15 min a day, five days, a week for 6 weeks. |
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| waitlist control | Active Comparator | Participants will be randomized to a waitlist group for six weeks. The waitlist control group will then be able to use the meditation app for six weeks as the primary intervention group |
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| Baseline physiology | Other | A subset of participants will not participate in the intervention. Only baseline fMRI and EEG data will be collected in these participants. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intervention | Behavioral | the digital meditation app will be installed on participants iPad or android. Lonely older adults will use the app five days a week for six weeks total. Neuroimaging will be performed before and after the intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the WHO-5 Well-Being Index | WHO-5 ranges from 0-25, with higher values indicating higher well-being | Change in well-being from baseline to directly after completing the intervention (6 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the 20-item UCLA loneliness scale | This scale ranges from 20-80, with higher values indicating higher loneliness | Change in loneliness from baseline to directly after completing the intervention (6 weeks) |
| Change in the General Anxiety Disorder-7 (GAD-7) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lorenzo Pasquini, PhD | University of California, San Francisco | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of California San Francisco | San Francisco | California | 94158 | United States |
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| ID | Term |
|---|---|
| D008722 | Methods |
| ID | Term |
|---|---|
| D008919 | Investigative Techniques |
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| waitlist control | Behavioral | Participants in the waitlist group will have to wait six weeks after being screened before being able to use the meditation app after the assessment of primary and secondary endpoints |
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| No Interventions | Other | No intervention. Only baseline fMRI and EEG assessment. |
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This scale ranges from 0-21, with higher values indicating higher anxiety |
| Change in anxiety from baseline to directly after completing the intervention (6 weeks) |
| Change in Psychological Stress Measure (PSM-9) | This scale ranges from 9-72, with higher values indicating higher stress | Change in stress from baseline to directly after completing the intervention (6 weeks) |
| Change in Patient Health Questionnaire (PHQ-9) | This scale ranges from 0-27, with higher values indicating higher depression | Change in depression from baseline to directly after completing the intervention (6 weeks) |