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More than half of all pediatric cancer in Korea are solid cancer. For the treatment of solid cancer, multidisciplinary methods such as surgery, chemotherapy, and radiation therapy are applied, and with the development of the treatment method, the treatment performance has improved dramatically, and the 5-year survival rate of more than 80% is currently recorded. Due to the improvement in survival rate, interest in side effects caused by cancer treatment itself is gradually increasing, and efforts to reduce them are increasing. Accordingly, it aims to contribute to improving the quality of life of pediatric solid cancer survivors. by developing a Korean-type early diagnosis and follow-up protocol of ototoxic hearing loss, which commonly occurs in pediatric solid cancer who have undergone chemotherapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pediatric solid cancer |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chemotherapy involving cisplatin or carboplatin | Other | Chemotherapy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patients with ototoxic hearing loss | Proportion of patients with ototoxic hearing loss in total patients | 1 year after the initiation of chemotherapy |
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Inclusion Criteria:
â‘ Solid cancer patients under the age of 19 receiving Platinum chemotherapy
â‘¡ Solid cancer patients under the age of 19 receiving 30 Gy or more head and neck radiation therapy
Exclusion Criteria:
â‘ Those who have received chemotherapy or radiation in the past
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Patients who are diagnosed as solid cancer and receive platinum chemotherapy
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| ID | Term |
|---|---|
| D034381 | Hearing Loss |
| ID | Term |
|---|---|
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D016190 | Carboplatin |
| ID | Term |
|---|---|
| D056831 | Coordination Complexes |
| D009930 | Organic Chemicals |
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