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This human application test was planned to evaluate the effectiveness and safety of immunodefinition compared to the placebo when the GCWB1176 was consumed for those whose white blood cell level was normal or somewhat decreased.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GCWB1176 | Experimental | 1 capsule once a day |
|
| Placebo | Active Comparator | 1 capsule once a day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lactococcus lactis | Dietary Supplement | 1 capsule once a day |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change amoust of NK Cell Activity | The comparison of the military comparison for the change before and after the intake of NK CELL Activity is analyzed using the PAIRED T-TEST, and the degree of change between the test group and the control at at each point is Two Sample T-Test or Wilcoxon Rank Sum Test It is conducted to evaluate whether there is a statistically significant difference. | week 0, 4 and 8 |
| Measure | Description | Time Frame |
|---|---|---|
| Change amoust of Cytokine analysis (IFN-γ, TNF-α, IL-4, IL-10, IL-12) | The comparison of the military in the before and after consumption is analyzed using the PAIIRED T-TEST, and the degree of change between the test group and the control group at each time is performed by performing the two sample T-test or the Wilcoxon Rank Sum Test according to whether the normality is satisfied. Evaluate if there is a significant difference. |
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Inclusion Criteria:
At the time of screening, 19 or 75 years
A person with a peripheral blood leukocyte level measured in Visit 1, 3x10^3 cells/μl or more, 8x10^3 cells/μl
Those who are more than one of the following standards
Those who had more than twice within one year of visiting 1 year.
{Common cold, acute tonsillitis, acute pharyngitis, acute laryngitis, acute rhinitis, etc.
Those who have stomatitis more than twice within 1 year of visit
Those with a stress awareness scale (PSS) 16 or more
A person who agrees to participate in this human application test before the start of the human test and writes a written consent form
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul St. Mary's Hospital, College of Medicine | Seoul | South Korea | ||||
| St. Vincent's Hospital, College of Medicine |
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| ID | Term |
|---|---|
| C008315 | maltodextrin |
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| maltodextrin |
| Other |
1 capsule once a day |
|
| week -2, 0, 4 and 8 |
| Change amoust of WBC Count analysis | The comparison of the military in the before and after consumption is analyzed using the PAIIRED T-TEST, and the degree of change between the test group and the control group at each time is performed by performing the two sample T-test or the Wilcoxon Rank Sum Test according to whether the normality is satisfied. Evaluate if there is a significant difference. | week -2, 0, 4 and 8 |
| Change amoust of FSS Count analysis | The comparison of the military in the before and after consumption is analyzed using the PAIIRED T-TEST, and the degree of change between the test group and the control group at each time is performed by performing the two sample T-test or the Wilcoxon Rank Sum Test according to whether the normality is satisfied. Evaluate if there is a significant difference. | week -2, 0, 4 and 8 |
| Change amoust of upper respiratory infection analysis | The comparison of the military in the before and after consumption is analyzed using the PAIIRED T-TEST, and the degree of change between the test group and the control group at each time is performed by performing the two sample T-test or the Wilcoxon Rank Sum Test according to whether the normality is satisfied. Evaluate if there is a significant difference. If there is a statistically significant difference between the military and clinically significantly significantly significant differences in demographic and lifestyle surveys, ANCOVA can be carried out as a covenant. | week -2, 0, 4 and 8 |
| Suwon |
| South Korea |