The aim of this study is to explore if STI technology, especially TMAD, plays an important role in evaluating left ventricular longitudinal systolic function and discriminating SICM in patients with sepsis. The investigators also intend to prove that TMAD may have predictive value in patients with sepsis, which is worthy of in-depth study to find strong evidence-based medical evidence for subsequent clinical practical applications.

In order to explore if STI technology, especially TMAD, plays an important role in evaluating left ventricular longitudinal systolic function and discriminating SICM in patients with sepsis, the investigators intend to explore that TMAD may have predictive value in patients with sepsis, which is worthy of in-depth study to find strong evidence-based medical evidence for subsequent clinical practical applications.

Inclusion Criteria:

• patients who are diagnosed as sepsis according to sepsis 3.0 criteria

Exclusion Criteria:

• patients with history of organic heart disease;
• patients with history of heart failure
• holder of cardiac implanted device;
• patients with history of atrial fibrillation;
• refusal to participate in the study

adult patients who are diagnosed as sepsis according to sepsis 3.0 criteria, excluding those with history of organic heart disease, heart failure, atrial fibrillation or holder of cardiac implanted device