A Phase 3, Randomized Study to Compare the Efficacy and Safety of Nemtabrutinib Versus Chemoimmunotherapy for Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Without TP53 Aberrations
A Phase 3, Randomized Study to Compare the Efficacy and Safety of Nemtabrutinib Versus Chemoimmunotherapy for Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Without TP53 Aberrations
Researchers are looking for new ways to treat people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). CLL and SLL are types of blood cancer. Researchers want to know if people who take nemtabrutinib compared to those who take the standard treatments in this study will live longer without their cancer growing, spreading or returning (progression free survival).
The main inclusion and exclusion criteria include but are not limited to the following:
Inclusion Criteria:
Exclusion Criteria:
Rio de Janeiro, 20231-050, Brazil
São Paulo, 01246-000, Brazil
Sofia, Sofia (stolitsa) 1797, Bulgaria
Plovdiv, 4002, Bulgaria
Chongqing, Chongqing Municipality 404000, China
Guangzhou, Guangdong 510515, China
Wuhan, Hubei 430022, China
Changsha, Hunan 410008, China
Suzhou, Jiangsu 215006, China
Tianjin, Tianjin Municipality 300020, China
Tianjin, Tianjin Municipality 300060, China
Hangzhou, Zhejiang 310003, China
Valledupar, Cesar Department 200001, Colombia
Hksar, Hong Kong
Eger, Heves County 3300, Hungary
Nyíregyháza, Szabolcs-Szatmár-Bereg 4400, Hungary
Kaunas, Kaunas County 50161, Lithuania
Ampang, Selangor 68000, Malaysia
Lublin, Lublin Voivodeship 20-081, Poland
Warsaw, Masovian Voivodeship 02-781, Poland
Gdansk, Pomeranian Voivodeship 80-952, Poland
Olsztyn, Warmian-Masurian Voivodeship 10-228, Poland
Kielce, Świętokrzyskie Voivodeship 25-734, Poland
Centurion, Gauteng 0181, South Africa
Kuilsriver, Western Cape 7580, South Africa
Kaohsiung City, 83301, Taiwan
Stanbul, Istanbul 34214, Turkey (Türkiye)
Suleymanpasa, Tekirdas 59100, Turkey (Türkiye)
Istanbul, 34722, Turkey (Türkiye)
Cherkassy, Cherkasy Oblast 18009, Ukraine
Ivano-Frankivsk, Ivano-Frankivsk Oblast 76008, Ukraine
Lviv, Lviv Oblast 79057, Ukraine
Kyiv, 03115, Ukraine