Colonisation Efficacy of a Probiotic Chewing Gum.

Colonisation Efficacy of a Probiotic Chewing Gum.

To evaluate the colonization efficacy (the ability of a probiotic bacteria to remain in the mouth) delivered in a chewing gum format. The chewing gum contains Streptococcus salivarius probiotic and the study is to be done in health adults.

This is a single blind, randomized controlled study to evaluate the colonization effectiveness of a chewing gum containing a commercially available probiotic bacterium. Participants will be randomly assigned to one of the two groups consuming chewing gum containing Streptococcus salivarius M18 over a 7-day period. Saliva samples will be collected at pre determined points (pre and post intervention). Colonization efficacy will be determined by enumerating the probiotic from the saliva samples using standard microbiological techniques.

Inclusion Criteria:

• In general, good health
• Practice good oral hygiene

Exclusion Criteria:

• Have a history of autoimmune disease or are immune compromised.
• Are on concurrent antibiotic therapy, or regular antibiotic use within last one week
• People with allergies or sensitivities to dairy.