Multiple myeloma patients with normal ability of communication and understanding will be enrolled. DT, GAD-7, PHQ-15 and PSQI scales are designed to assess the mental health status of the patients. Demographic and disease data of patients will be collected as well. The main aim is to explore the factors affecting the mental health of myeloma patients.

Inclusion Criteria:

1. Patients with symptomatic multiple myeloma were diagnosed according to the criteria of Chinese multiple myeloma diagnosis and treatment guidelines (revised in 2022).
2. Age ≥18 years, with junior high school education or above. Patients have normal ability of communication and understanding.
3. Informed consent has been signed.

Exclusion Criteria:

1. Who has kinship with other enrolled patients.
2. Life expectancy of< 6 months.

The patients will be recruited form 14 medical centers.