This study would have as a starting point the results of a request carried out by the Medical Service Grand Est of the Health Insurance aiming to evaluate the number of boxes of PPI reimbursed in town pharmacy, in patients over 75 years old in the Grand Est of France from 01/01/2018 to 31/12/2018.

It aims to highlight and quantify a possible inappropriate use of PPIs in private practice.

Inclusion criteria:

• Patient over 75 years of age
• Patient with a PPI in the initial prescription
• Patient seen at least once between 01/01/2018 and 31/11/2019 in the general practice
• Patient who has not expressed his opposition, after information, to the reuse of his data for the purpose of this research.

Exclusion criteria:

• Patient having expressed his opposition to participate in the study
• Impossibility to give the patient informed information (difficulties in understanding the subject, ...)
• Patient under legal protection
• Patient under guardianship or curatorship
• Patient who is no longer followed up in the office following an entry into an institution (EHPAD)

Patient, over 75 years of age, with a PPI in the initial prescription