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This megastudy is a massive randomized controlled trial. By randomizing participants to 10 different intervention conditions simultaneously, the investigators will be able to compare the effectiveness of different interventions to one another and to a control group (in which individuals will only receive the usual communications from their partner organization) to identify which interventions significantly increase vaccination rates. Pharmacy customers will be randomly assigned to receive one of the interventions designed by team scientists to encourage vaccination or to a control group. The baseline intervention will be based on the top-performing SMS intervention identified in the investigators previous megastudies on encouraging vaccination (Milkman et al., 2021b, 2022). Pharmacy customers will receive SMS messages conveying that a COVID booster vaccine is reserved or waiting for them at the pharmacy. Additional behavioral science messaging strategies will be tested by building off of this baseline intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Holdout control condition with no message | No Intervention | Participants will only receive the standard pharmacy messaging. | |
| Control condition with "waiting for you" message | Experimental | This control condition will use the text message that we've found to be the best performing in our last mega-study of vaccine text messages to recommend a COVID vaccination. |
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| Control condition with "waiting for you" message with a GIF | Experimental | This control condition will use the text message that we've found to be the best performing in our last mega-study of vaccine text messages and includes a GIF to recommend a COVID vaccination. |
|
| Planning message recommending same time/location as last vaccination | Experimental | This condition will use a text message recommending the same time and location as the participant's last vaccination to get a COVID vaccination. |
|
| Message from local pharmacy team | Experimental | This condition will use a text message from the participant's local pharmacist recommending a COVID vaccination. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| COVID Booster text messages | Behavioral | Participants will receive text messages per descriptions listed in the arms. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Patient uptake of the COVID bivalent booster | Whether patients receive a bivalent COVID booster at the pharmacy in question | During the 30 days after receiving the SMS/MMS intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Patient uptake of the COVID bivalent booster | Whether patients receive a bivalent COVID booster at the pharmacy in question | 60 days after receiving the SMS/MMS intervention |
| Patient uptake of the COVID bivalent booster |
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Inclusion Criteria:
• Patient of a large retail pharmacy that has opted into receving SMS messages from the pharmacy and has received their primary COVID vaccination series.
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | United States |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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Participants will be randomly assigned to the different arms.
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As treated participants will receive text messages, there is no scope for blinding. Care providers will not be made aware of subjects' participation in the study, or assigned treatment arms. The study team will only receive data on subjects' assigned arms and outcomes at the end of the study.
|
| Message including link to resources combating misinformation | Experimental | This condition will use a text message including a link to to resources combating misinformation and then recommend a COVID vaccination. |
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| Message including link to resources combating misinformation with a GIF | Experimental | This condition will use a text message including a link to to resources combating misinformation and then recommend a COVID vaccination and will include a GIF. |
|
| Message offering free round trip ride to the pharmacy | Experimental | This condition will use a text message offering a free round trip ride to the pharmacy to get a COVID vaccination. |
|
| Message communicating latest data on COVID transmission in patient's area | Experimental | This condition will use a text message informing the participant of the latest data on COVID transmission in participant's area and recommend a COVID vaccination. |
|
| Message encouraging vaccination in preparation for the holidays | Experimental | This condition will use a text message to encourage a COVID vaccination in preparation for the holidays. |
|
| Message conveying the CDC recommends vaccination | Experimental | This condition will use a text message to encourage a COVID vaccination by conveying the CDC recommends vaccination. |
|
Whether patients receive a bivalent COVID booster at the pharmacy in question
| 90 days after receiving the SMS/MMS intervention |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |