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A retrospective analysis of data, using the Hospital records of all the patients who underwent cholecystectomy for benign conditions at Osmania General Hospital in a year (2019).
A retrospective analysis of hospital records of patients who underwent Cholecystectomy in a year duration (2019) for any benign condition, diagnosed and confirmed histopathologically as Gallbladder Malignancy.
There are a total of one hundred and eighty patients who underwent cholecystectomy at our hospital (Osmania General Hospital) in 2019, out of which seven patients' histopathological diagnosis was gall bladder malignancy. We reviewed all the case's history, cross-checked the histopathological slides, and confirmed the diagnosis. To avoid the bias of covid-19 pandemic in surgical practice we confined the patient records to the pre-pandemic period of one-year duration (2019).
A total of 180 patients underwent cholecystectomy for various benign conditions in one year, out of which seven patients confirmed histopathologically with Gallbladder malignancy.
Total no of patients : 180 Diagnosed with malignancy : 7 percentage 3.8%
Among these seven, three patients converted from laparoscopic to open procedure for difficulty with resection, two patients are posted for surgery considering empyema of gall bladder preoperatively, one patient in view of gall bladder perforation, and for two patients preoperative diagnosis was gall bladder polyp.
Converted from Lap to Open: 3 Pre-op GB Polyp : 2 Perforated GB : 1 Empyema GB : 2
Only one patient is 40 years old and others are more than 50 years, and two of them are males.
Total : 7 100% Males : 2 28.5% Females : 5 71.5%
Out of a total of 180 patients who underwent cholecystectomy, 117 are females and 63 are males
Total : 180 Males : 63 Females : 117
Out of 180, the age distribution is as follows
Age. Percentage 20 - 29 0 30 - 39 0 40 - 49 0.005 >50. 99.99
It implies that the malignancy rate increases with an increase in the patient's age more than 50years and also with gender (Females > males).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients who underwent cholecystectomy for benign conditions | In those who underwent cholecystectomy for benign conditions, the histopathological analysis showed the malignancy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cholecystectomy, extended cholecystectomy | Procedure | Cholecystectomy and histopathological evaluation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Diagnosed with Gallbladder malignancy | Those who underwent cholecystectomy for benign conditions are diagnosed with gallbladder malignancy | For one year |
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Inclusion Criteria: All patients who underwent cholecystectomy for benign conditions -
Exclusion Criteria: All those who already diagnosed with gallbladder malignancy
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All the patients who underwent cholecystectomy for benign conditions like gall stones, polyps,. Etc,.
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| Name | Affiliation | Role |
|---|---|---|
| Sathaiah Dadi, MS Gen Surg | Osmania Medical College | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Osmania General Hospital | Hyderabad | Telangana | 500012 | India |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Aug 8, 2022 | Nov 2, 2022 | Prot_SAP_000.pdf |
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| ID | Term |
|---|---|
| D005706 | Gallbladder Neoplasms |
| D011127 | Polyps |
| D042882 | Gallstones |
| D009369 | Neoplasms |
| ID | Term |
|---|---|
| D001661 | Biliary Tract Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D001660 | Biliary Tract Diseases |
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| ID | Term |
|---|---|
| D002763 | Cholecystectomy |
| ID | Term |
|---|---|
| D001662 | Biliary Tract Surgical Procedures |
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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| D004066 | Digestive System Diseases |
| D005705 | Gallbladder Diseases |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D002769 | Cholelithiasis |
| D041761 | Cholecystolithiasis |
| D002137 | Calculi |