A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease | NCT05595642 | Trialant

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease | NCT05595642 | Trialant

Ages Eligible for Study: Adult (18-64)Older Adult (65+)
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Eligibility Criteria: Inclusion Criteria

Documented COPD diagnosis for ≥ 12 months

History of frequent exacerbations, defined as having had 2 or more moderate or severe COPD exacerbations within 12 months prior to screening

Post-bronchodilator FEV1 ≥ 20% and < 80% of predicted at screening

Post-bronchodilator FEV1/FVC < 0.70 at screening

Modified Medical Research Council (dyspnea scale) (mMRC) score ≥ 2

Current tobacco smoker or former smoker with a history of smoking ≥ 10 pack-years

On optimized COPD maintenance therapy as defined below for ≥ 12 months prior to screening, and stable on current therapy for at least 4 weeks prior to screening: Inhaled corticosteroid (ICS) plus long-acting beta-agonist (LABA), Long-acting muscarinic antagonist (LAMA) plus LABA, ICS plus LAMA plus LABA

Chest X-ray or computed tomography (CT) scan within 6 months prior to screening or chest X-ray during the screening period that confirms the absence of clinically significant lung disease besides COPD

Exclusion Criteria

Current documented diagnosis of asthma

History of clinically significant pulmonary disease other than COPD

Diagnosis of 1-antitrypsin deficiency

History of long-term treatment with oxygen at > 4.0 liters/minute

Lung volume reduction surgery or procedure within 12 months prior to screening

Individuals participating in, or scheduled for, an intensive COPD rehabilitation program (participants who are in the maintenance phase of a rehabilitation program are eligible)

History of lung transplant

Any infection that resulted in hospital admission for ≥ 24 hours and/or treatment with oral, IV, or IM antibiotics within 4 weeks prior to or during screening

Upper or lower respiratory tract infection within 4 weeks prior to or during screening

Treatment with oral, IV, or IM corticosteroids within 4 weeks prior to initiation of study drug

Initiation of or change in non-biologic immunomodulatory or immunosuppressive therapy within 3 months prior to screening

Unstable cardiac disease, myocardial infarction, or New York Heart Association Class III or IV heart failure within 12 months prior to screening

University of Alabama at Birmingham

Birmingham, Alabama 35294, United States

SEC Clinical Research LLC - Dothan 2 - ClinEdge - PPDS

Dothan, Alabama 36305, United States

Pulmonary Associates PA

Glendale, Arizona 85306-4669, United States

AES - DRS - Synexus Clinical Research US, Inc. - Tucson

Tucson, Arizona 85741-3118, United States

Kern Research

Bakersfield, California 93301, United States

Allergy & Asthma Medical Group of the Bay Area

Walnut Creek, California 94598, United States

Finlay Medical Research Corporation

Greenacres City, Florida 33467-2979, United States

San Marcus Research Clinic Inc.

Miami, Florida 33014, United States

Oceane7 Medical & Research Center, Inc.

Miami, Florida 33144-2155, United States

Avantis Clinical Research, LLC

Miami, Florida 33155-3265, United States

Research Institute of South Florida Inc

Miami, Florida 33173, United States

Diverse Clinical Research, LLC

Miami, Florida 33175-3434, United States

Central Florida Pulmonary Group, PA

Orlando, Florida 32803, United States

AES - DRS - Synexus Clinical Research US, Inc. - The Villages

The Villages, Florida 32162-7116, United States

AES - DRS - Synexus Clinical Research US, Inc. - Atlanta

Atlanta, Georgia 30328, United States

Allergy Center at Brookstone Research - Centricity Research - HyperCore - PPD

Columbus, Georgia 31904-2954, United States

Pivotal Research Solutions

Stonecrest, Georgia 30038-2649, United States

ASHA Clinical Research - ClinEdge - PPDS

Hammond, Indiana 46324-2213, United States

The Research Group of Lexington, LLC

Lexington, Kentucky 40504, United States

Best Clinical Trials

New Orleans, Louisiana 70115, United States

Paul A. Shapero, MD, PA

Bangor, Maine 04401-5691, United States

Pulmonary Research Institute of Southeast Michigan

Farmington Hills, Michigan 48336-2817, United States

Flushing Road Internal Medicine and Pediatrics - F

Flint, Michigan 48504-4730, United States

Revive Research Institute

Lathrup Village, Michigan 48076, United States

Oakland Medical Research Center

Troy, Michigan 48085-5524, United States

Washington University School of Medicine in St. Louis

St Louis, Missouri 63110, United States

Nebraska Medical Research Institute, Inc. - CRN

Bellevue, Nebraska 68123-4318, United States

Machuca Family Medicine

Las Vegas, Nevada 89104-3953, United States

Renown Regional Medical Center Hospital

Reno, Nevada 89502-1576, United States

Hassman Research Institute - HRI - Berlin - CenExel - PPDS

Marlton, New Jersey 08053, United States

AES - DRS - Synexus Clinical Research US, Inc. - New York

New York, New York 10017-4008, United States

Research Carolina Elite

Denver, North Carolina 28037-7929, United States

Pulmonix LLC

Greensboro, North Carolina 27403, United States

Advanced Respiratory and Sleep Medicine, PLLC

Huntersville, North Carolina 28078, United States

Southeastern Research Center

Winston-Salem, North Carolina 27103-4029, United States

OK Clinical Research

Edmond, Oklahoma 73034-3258, United States

The Oregon Clinic

Portland, Oregon 97213, United States

Clinical Research Associates Of Central Pa , Llc

Altoona, Pennsylvania 16602, United States

Allergy & Clinical Immun Assoc

Pittsburgh, Pennsylvania 15241, United States

Medtrial, LLC

Columbia, South Carolina 29204, United States

Velocity Clinical Research - Gaffney - PPDS

Gaffney, South Carolina 29340-4737, United States

ClinSearch, LLC

Chattanooga, Tennessee 37421, United States

Clinical Trials Center of Middle Tennessee

Franklin, Tennessee 37067-5603, United States

Tennessee Comprehensive Lung & Sleep Center

Hendersonville, Tennessee 37075-3085, United States

TTS Research

Boerne, Texas 78006, United States

Corsicana Medical Research

Corsicana, Texas 75110-2471, United States

Trio Clinical Trials

Houston, Texas 77008, United States

Baylor College of Medicine Medical Center

Houston, Texas 77030, United States

Biopharma Informatic - Park Row - PPDS

Houston, Texas 77084, United States

R & H Clinical Research

Katy, Texas 77494-2031, United States

University of Vermont Medical Center

Burlington, Vermont 05401, United States

Western Washington Medical Group

Everett, Washington 98208, United States

Allergy Asthma and Sinus Center-Greenfield

Greenfield, Wisconsin 53228-3467, United States

Consultorios Medicos Organizacion de Buen Ayre SRL

Buenos Aires, 12345, Argentina

Nexo Salud Investigacion Clinica - Riobamba 429

Buenos Aires, C1025, Argentina

CINME S.A. ? Centro de Investigaciones Metabolicas - Rx Trials LLC

Buenos Aires, C1027AAP, Argentina

Fundacion Faicep

Buenos Aires, C1122AAK, Argentina

Instituto de Investigaciones En Alergia Y Enfermedades Respiratorias

Buenos Aires, C1425, Argentina

AES - AS - Glenny Corp. S.A. Buenos Aires

Buenos Aires, C1430, Argentina

Centro de Medicina Respiratoria

Concepción del Uruguay, 3260, Argentina

Sanatorio de la Canada

Córdoba, X5000BSQ, Argentina

Framingham Centro Medico

La Plata, 1900, Argentina

Centro Medico Capital

La Plata, 1904, Argentina

Centro Platense en Investigaciones Respiratorias

La Plata, B1900BNN, Argentina

Centro Medico Dharma

Mendoza, M5500AYB, Argentina

Centro Privado de Medicina Respiratoria

Paraná, 3100, Argentina

Sala de primeros auxilios Alberto Mignaburu

Ranelagh, Berazategui, 1886, Argentina

Instituto Medico de la Fundacion Estudios Clinicos

Rosario, S2000DEJ, Argentina

Servicio de Investigacion de Patologias Alergicas-Instituto ABC

Rosario, S2013JKR, Argentina

Sanatorio Parque de Rosario

Rosario, S2013KZD, Argentina

Centro Modelo de Cardiologia

San Miguel de Tucumán, 4000, Argentina

Centro Medico San Nicolas Grupo Orono

San Nicolás de los Arroyos, B2900, Argentina

CEPROSS- Centro Profesional San Salvador

San Salvador, E3218CHH, Argentina

Instituto Del Buen Aire

Santa Fe, S3000ASF, Argentina

Centro de Diagnostico Y Rehabilitacion

Santa Fe, S3000, Argentina

Institute for Respiratory Health - Midland

Midland, South Australia 6056, Australia

Ordination Dr. Robert Voves

Feldbach, 8330, Austria

Ordination fur Lungenkrankheiten

Linz, 4020, Austria

AZ Sint-Jan Brugge-Oostende

Bruges, 8000, Belgium

Universitair Ziekenhuis Brussel

Brussels, 1090, Belgium

Cliniques Universitaires Saint-Luc

Brussels, 1200, Belgium

CHU de Liège

Liège, 4000, Belgium

L2IP ?Instituto de Pesquisas Clínicas Ltda.

Brasília, Federal District 70200-730, Brazil

Santa Casa de Misericordia de Belo Horizonte - PPDS

Belo Horizonte, Minas Gerais 30150-221, Brazil

LMK Servicos Medicos SS

Porto Alegre, Rio Grande do Sul 90480-000, Brazil

Hospital Sao Lucas Da Pontificia Universidade Catolica Do Rio Grande Do Sul (PUCRS)

Porto Alegre, Rio Grande do Sul 90610-000, Brazil

Faculdade de Medicina do ABC - FMABC

Santo André, São Paulo 09060-650, Brazil

CEMEC - Centro Multidisciplinar de Estudos Clínicos

São Bernardo do Campo, São Paulo 09715-090, Brazil

IBPCLIN Instituto Brasil de Pesquisa Clinica

Rio de Janeiro, 20241-180, Brazil

Instituto do Coracao - HCFMUSP

São Paulo, 05403-000, Brazil

Multiprofile Hospital for Active Treatment Puls AD PPDS

Blagoevgrad, 2700, Bulgaria

Multiprofile Hospital For Active Treatment Sveta Ekaterina - Dimitrovgrad EOOD

Dimitrovgrad, 6400, Bulgaria

Multiprofile Hospital For Active Treatment Dr. Tota Venkova JSC

Gabrovo, 5300, Bulgaria

Medical Center Hera EOOD

Montana, 3400, Bulgaria

Multiprofile Hospital for Active Treatment Plovdiv

Plovdiv, 4003, Bulgaria

Multiprofile Hospital for Active Treatment Sv. Ivan Rilski- Razgrad AD

Razgrad, 7200, Bulgaria

Multiprofile Hospital for Active Treatment Shumen

Shumen, 9700, Bulgaria

Multiprofile Hospital for Active Treatment - Silistra AD

Silistra, 7500, Bulgaria

Multiprofile Hospital For Active Treatment - Dr. Bratan Shukerov AD

Smolyan, 4700, Bulgaria

Fifth Multiprofile Hospital for Active Treatment - Sofia EAD

Sofia, 1233, Bulgaria

Diagnostic-Consultative Center Aleksandrovska EOOD

Sofia, 1431, Bulgaria

Diagnostic- Consultative Center Convex EOOD

Sofia, 1680, Bulgaria

AES DRS Medical Center Synexus Sofia EOOD

Sofia, 1784, Bulgaria

Diagnostic Consultative Centre Mladost?M OOD

Varna, 9020, Bulgaria

Medical Center Tara OOD

Veliko Tarnovo, 5000, Bulgaria

Edmonton Respiratory Consultants

Edmonton, Alberta T5J 3S9, Canada

Synergy Respiratory & Cardiac Care - Synergy Wellness Centre Location

Sherwood Park, Alberta T8H 0N2, Canada

Vancouver General Hospital

Vancouver, British Columbia V5Z 1M9, Canada

Dynamic Drug Advancement Ltd.

Ajax, Ontario L1S 2J5, Canada

Inspiration Research

Toronto, Ontario M5T 3A9, Canada

Dr. Syed Anees Medicine Profession Corporation

Windsor, Ontario N8X 1T3, Canada

Dr Anil Dhar Professional Medicine Corporation

Windsor, Ontario N8X 5A6, Canada

Recherche GCP Research

Montreal, Quebec H1Y 3H5, Canada

Clinique de pneumologie et du sommeil de Lanaudiere

Saint-Charles-Borromée, Quebec J6E 2B4, Canada

Centre Hospitalier de l'Universite Laval

Québec, G1V 4G5, Canada

Centro Respiratorio Integral LTDA. (CENRESIN)

Pavie Gallegos, 2340000, Chile

Oncocentro APYS

Viña del Mar, 2520598, Chile

Fundacion Medica San Cristobal

Vitacura, 7630000, Chile

The Third Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong 510150, China

The First Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong 510160, China

Affiliated Hospital of Guangdong Medical University

Zhanjiang, Guangdong 524001, China

Affiliated Hospital of Zunyi Medical University

Zunyi, Guizhou 563000, China

The First People's Hospital of Lian Yun Gang

Lianyungang, Jiangsu 222061, China

Beijing Chaoyang Hospital Capital Medical University

Beijing, 100020, China

China-Japan Friendship Hospital

Beijing, 100029, China

Beijing Jingmei Group General Hospital

Beijing, 100042, China

Beijing Hospital

Beijing, 100730, China

Peking University Shougang Hospital

Beijing, China

The First Hospital of Jilin University

Changchun, 130021, China

The First Hospital of Changsha

Changsha, 410005, China

The Third Hospital of Changsha

Changsha, China

West China Hospital, Sichuan University

Chengdu, 610041, China

Chengdu Fifth People's Hospital

Chengdu, 611130, China

The Southwest Hospital of Army Medical University

Chongqing, 400038, China

Army Medical Center of PLA(Daping Hospital)

Chongqing, 400042, China

Guangzhou First People's Hospital

Guangzhou, 510180, China

Hangzhou First People's Hospital

Hangzhou, 310006, China

Anhui Chest Hospital

Hefei, 230022, China

Huizhou Central People's Hospital

Huizhou, 516001, China

Taizhou Hospital of Zhejiang Province

Linhai, 317000, China

Jiangxi Provincial People's Hospital

Nanchang, 330006, China

Zhongda Hospital Southeast University

Nanjing, 210009, China

Jiangxi Pingxiang People's Hospital

Pingxiang, 337055, China

Huadong Hospital Affiliated to Fudan University

Shanghai, 200000, China

Shengjing Hospital of China Medical University

Shenyang, 110004, China

Tianjin Medical University General Hospital

Tianjin, 300052, China

Central Hospital of Wuhan

Wuhan, China

Wuxi People's Hospital

Wuxi, 214023, China

Jiangyin People's Hospital

Wuxi, 214400, China

Xi'an International Medical Center Hospital

Xi'an, 710100, China

Zhongshan Hospital Xiamen University

Xiamen, 361004, China

Xinxiang First People's Hospital

Xinxiang, 453000, China

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, China

Yangzhou First People?s Hospital

Yangzhou, 225001, China

The Fifth Affiliated Hospital Sun Yat-Sen University

Zhuhai, 519001, China

Zigong First People's Hospital

Zigong, 643036, China

Plicní ambulance MUDr. I. Cierná Peterová s.r.o.

Brandýs nad Labem-Stará Boleslav, 250 01, Czechia

Fakultni nemocnice Hradec Kralove

Hradec Králové, 500 05, Czechia

Odborna plicni ambulance Opava s.r.o

Opava, 746 01, Czechia

Ordinace chorob plicních s.r.o.

Prague, 110 00, Czechia

AES - DRS - Synexus Czech s.r.o.

Prague, 120 00, Czechia

Nemocnice Tabor, a.s.

Tábor, 390 03, Czechia

Plicni stredisko Teplice s.r.o.

Teplice, 415 01, Czechia

Naestved Sygehus

Næstved, 4700, Denmark

Sjaellands Universitetshospital, Roskilde

Roskilde, 4000, Denmark

Sas Clinique De L Europe - Amiens

Amiens, 80090, France

Hopital Calmette

Lille, 59000, France

Groupe Hospitalier Cochin St Vincent de Paul La Roche Guyon

Paris, 75014, France

Hopital Haut Leveque

Pessac, 33604, France

Velocity Clinical Research Leipzig GmbH

Lübeck, Schleswig-Holstein 23552, Germany

Praxis fur Kardiologie und Pneumologie Dr. med. Karin Forster

Berlin, 10367, Germany

Studienpraxis Berlin-Brandenburg, Berlin

Berlin, 12157, Germany

AES - DRS - Synexus Berlin Research Centre

Berlin, 12627, Germany

Lungenzentrum Darmstadt

Darmstadt, 64283, Germany

Universitaetsklinikum Frankfurt

Frankfurt, 60596, Germany

Praxisgem. Dres. Schmoller und Ehlers

Hamburg, 22299, Germany

Pneumologicum

Hanover, 30173, Germany

University Clinic Heidelberg

Heidelberg, 69120, Germany

Lungenfachklinik Immenhausen

Immenhausen, 34376, Germany

BAG Prof. Dr. G. Hoheisel Dr. A. Bonitz

Leipzig, 04299, Germany

SMO.MD GmbH

Magdeburg, 39120, Germany

Praxis Dr. med. Jan Feimer

München, 80539, Germany

Institut fur klinische Forschung GmbH

Neu-Isenburg, 63263, Germany

framol-med GmbH

Rheine, 48431, Germany

Klinikum Rosenheim

Rosenheim, 83022, Germany

Evangelismos General Hospital of Athens

Athens, 106 76, Greece

Navy Hospital of Athens

Athens, 115 21, Greece

University General Hospital of Heraklion

Heraklio, 711 10, Greece

University General Hospital of Ioannina

Ioannina, 455 00, Greece

Iatriko Palaiou Falirou

Palaió Fáliro, 175 62, Greece

Georgios Papanikolaou General Hospital of Thessaloniki

Thessaloniki, 570 10, Greece

Benyovszky Medical Center

Budapest, 1089, Hungary

Omnimodus Elixír Kft.

Csorna, 9300, Hungary

Paarthiv Lung Care Center

Hyderabad, Andhra Pradesh 500018, India

Yashoda Hospitals Hitec City

Hyderabad, Andhra Pradesh 500084, India

GMERS Medical College and Hospital, Sola

Ahmedabad, Gujarat 380059, India

ESIC Medical College and Hospital - Faridabad

Faridabad, Haryana 121012, India

Karnataka Medical College and Research Institute, Hubballi;Department of Medicine

Hubballi, Karnataka 580021, India

Shree Hospital And Critical Care Centre

Nagpur, Maharashtra 044009, India

Kothrud Hospital

Pune, Maharashtra 411038, India

Sawai Man Singh Hospital and Medical College

Jaipur, Rajasthan 302004, India

Maharaja Agrasen Super Speciality Hospital

Jaipur, Rajasthan 302039, India

Jawaharlal Nehru Medical College (JNMC)

Aligarh, Uttar Pradesh 202002, India

Apollo Spectra Hospital

Kanpur, Uttar Pradesh 208001, India

MV Hospital and Research Centre

Lucknow, Uttar Pradesh 226003, India

Soroka University Medical Centre

Beersheba, 8410101, Israel

Rambam Medical Center - PPDS

Haifa, 3109601, Israel

Lady Davis Carmel Medical Center

Haifa, 3436212, Israel

Hadassah Medical Center

Jerusalem, 9112001, Israel

Meir Medical Center

Kfar Saba, 4428164, Israel

Presidio Ospedaliero Santa Maria della Speranza

Battipaglia, Campania 84091, Italy

Azienda Ospedaliera Dei Colli

Naples, Campania 80131, Italy

Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant' Anna

Ferrara, Emilia-Romagna 44121, Italy

Fondazione IRCCS Policlinico San Matteo di Pavia

Pavia, Lombardy 27100, Italy

Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele

Catania, Sicily 95123, Italy

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

Palermo, Sicily 90127, Italy

Makita Hospital

Sapporo, Hokkaido 001-0901, Japan

Miura Medical Clinic

Miura-shi, Kanagawa 238-0111, Japan

Kitasato University Hospital

Sagamihara-shi, Kanagawa 252-0375, Japan

Yokohama Front Clinic

Yokohama, Kanagawa 221-0835, Japan

Yokohama-Gumyouji Kokyuukinaika Naika Clinic

Yokohama, Kanagawa 232-0066, Japan

Matsusaka City Hospital

Matsusaka-Shi, Mie-ken 515-8544, Japan

University of the Ryukyus Hospital

Ginowan-shi, Okinawa 901-2725, Japan

Fujieda Municipal General Hospital

Fujieda-Shi, Shizuoka 426-8677, Japan

Yamaguchi University Hospital

Ube-shi, Yamaguchi 755-8505, Japan

Asahikawa Medical Center

Asahikawa-shi, 070-0901, Japan

Fukuoka University Chikushi Hospital

Chikushino-shi, 818-8502, Japan

National Hospital Organization Kyushu Medical Center

Chuo-ku, Fukuoka-shi, 810-8563, Japan

Fukuwa Clinic

Chūōku, 104-0031, Japan

Fukuoka University Hospital

Fukuoka, 814-0180, Japan

Nishi Fukuoka Hospital

Fukuoka-Shi Nishi-Ku, 819-0055, Japan

Terada Respiratory and Internal Clinic

Himeji, 670-0849, Japan

Hiroshima Prefectural Hospital

Hiroshima, 734-8530, Japan

Ishikawa Prefectural Central Hospital

Ishikawa, 920-8530, Japan

National Hospital Organization Minami Kyoto Hospital

Jōyō, 610-0113, Japan

Kagoshima Kouseiren Hospital

Kagoshima, 890-0062, Japan

Kagoshima University Hospital

Kagoshima, 890-8520, Japan

Yokohama City University Medical Center

Kanagawa, 232-0024, Japan

Osaka-Minami Medical Center

Kawachinagano-Shi, 586-8521, Japan

Kiryu Kosei General Hospital

Kiryū, 376-0024, Japan

Kishiwada City Hospital

Kishiwada, 596-0822, Japan

Hospital of the University of Occupational and Environmental Health,Japan

Kitakyushu-shi, 807-8556, Japan

Juntendo Tokyo Koto Geriatric Medical Center

Kōtō City, 136-0075, Japan

Saiseikai Kumamoto Hospital

Kumamoto, 861-4101, Japan

Rakuwakai Otowa Hospital

Kyoto, 607-8062, Japan

National Hospital Organization Kyoto Medical Center

Kyoto, 612-8555, Japan

Machida Municipal Hospital

Machida-shi, 194-0023, Japan

Dokkyo Medical University Hospital

Mibu-Machi, 321-0293, Japan

Fukushima Medical University Hospital

Miyagi, 960-1295, Japan

Nagoya Ekisaikai Hospital

Nagoya, 454-8502, Japan

Kojunkai Social Medical Corporation Daido Clinic

Nagoya-shi Minami-ku, 457-8511, Japan

National Hospital Organization Ibarakihigashi National Hospital

Naka-gun, 319-1113, Japan

Niigata City General Hospital

Niigata, 950-11977, Japan

National Hospital Organization Okayama Medical Center

Okayama, 701-1192, Japan

Okayama Rosai Hospital

Okayama-Shi Minami-ku, 702-8055, Japan

Omuta National Hospital

Omuta, 837-0911, Japan

Izumi City General Hospital

Osaka, 594-0073, Japan

Oita Medical Center

Ōita, 870-0263, Japan

National Hospital Organization - Sagamihara National Hospital

Sagamihara-shi Minami-ku, 252-0392, Japan

Sakaide City Hospital

Sakaidechō, 762-0043, Japan

NHO Kinki-Chuo Chest Medical Center

Sakaishi, 591-8555, Japan

Japan Community Health Care Organization Hokkaido Hospital

Sapporo, 062-8618, Japan

Idaimae Minami 4-Jo Internal Medicine

Sapporo-shi Chuo-ku, 064-0804, Japan

Shizuoka City Shizuoka Hospital

Shizuoka, 424-0911, Japan

Iwata City Hospital

Shizuoka, 438?8550, Japan

Kamei Internal Medicine and Respiratory Clinic

Takamatsu, 761-8073, Japan

National Hospital Organization Takasaki General Medical Center

Takasaki, 370-0829, Japan

Minami Wakayama Medical Center

Tanabe, 646-8558, Japan

Tokyo-Eki Center-building Clinic

Tokyo, 103-0027, Japan

Nihon University Itabashi Hospital

Tokyo, 173-8610, Japan

Japanese Red Cross Medical Center

Tokyo, Japan

Toyama Prefectural Central Hospital

Toyama, 930-8550, Japan

Yamagata University Hospital

Yamagata, 990-9585, Japan

Nagata Hospital

Yanagawa, 832-0059, Japan

Showa University Fujigaoka Hospital

Yokohama-shi Aoba-ku, 227-8501, Japan

Kanagawa Cardiovascular and Respiratory Center

Yokohama-shi Kanazawa-ku, 236-0051, Japan

National Hospital Organization - Yokohama Medical Center

Yokohama-Shi Totsuka-Ku, 245-8575, Japan

Sanyudo Hospital

Yonezawa, 992-0033, Japan

KEMRI-MTWAPA Clinical Trial Site

Kilifi, Coast 80108, Kenya

Clinical Research Health Network (CREA-N)

Machakos, 90100, Kenya

KEMRI CRDR Clinical Research Clinic Nairobi

Nairobi, 00100, Kenya

University of Nairobi Clinical Research Centre

Nairobi, Kenya

Center for Research In Tropical Medicine and community development

Thika, 01000, Kenya

Daugavpils Regional Hospital

Daugavpils, LV-5417, Latvia

Pauls Stradins Clinical University Hospital

R?ga, LV-1002, Latvia

Riga 1st Hospital

Riga, LV-1001, Latvia

ConsiliumMedicum

Riga, LV-1010, Latvia

Postgraduate Medical Training Institute University of Latvia

Riga, LV-1011, Latvia

Meander Medisch Centrum

Amersfoort, 3813 TZ, Netherlands

Martini Ziekenhuis

Groningen, 9728 MG, Netherlands

Zuyderland Medisch Centrum - Heerlen

Heerlen, 6419PC, Netherlands

Greenlane Clinical Centre

Auckland, 1051, New Zealand

Dunedin Hospital

Dunedin, 9016, New Zealand

Waikato Hospital

Hamilton, 3248, New Zealand

P3 Research - Kapiti - PPDS

Waikanae Beach, 05036, New Zealand

Manila Central University-Filemon D Tanchoco Medical Foundation

Caloocan, 1442, Philippines

CARE CT Group Inc.

Dasmariñas, 4114, Philippines

Healthlink Medicalsurgicaldental Clinic and Diagnostic Center

Iloilo City, 5000, Philippines

West Visayas State University Medical Center

Iloilo City, 5000, Philippines

Mary Mediatrix Medical Center

Lipa City, 4217, Philippines

Philippine Heart Center

Quezon City, 1100, Philippines

Quirino Memorial Medical Center

Quezon City, 1109, Philippines

CenterMed Sp. z o.o.

Tarnów, Lesser Poland Voivodeship 33-100, Poland

AppleTreeClinics Network Sp. z o.o.

Lodz, Lódzkie 90-349, Poland

Centrum Medycyny Oddechowej Mroz sp. j.

Bia?ystok, 15-044, Poland

Vitamed Galaj i Cichomski sp.j.

Bydgoszcz, 85-079, Poland

Medical Center Kermed

Bydgoszcz, 85-231, Poland

Centrum Medyczne Lukamed Joanna Luka-Wendrowska

Chojnice, 89-600, Poland

Synexus Polska Sp. z o.o. Oddzial w Gdyni

Gdynia, 81-537, Poland

Centrum Medyczne CLW-med Aneta Cichomska , Joanna Luka -Wendrowska

Grudzadz, 86-300, Poland

Prywatny Gabinet Pulmonologiczny Joanna Nowacka-Apiyo

Grudziądz, 86-300, Poland

Centrum Medyczne Katowice - PRATIA - PPDS

Katowice, 40-081, Poland

Prywatna Praktyka Lekarska Adam Smialowski

Ksawerów, 95-054, Poland

AES - DRS - Synexus Polska Sp. Z o.o. Oddzial w Lodzi

Lodz, 90-127, Poland

Clinical Best Solutions - Lublin

Lublin, 20-078, Poland

NZOZ Przychodnia Alergologiczno-pulmonologiczna

Lublin, 20-089, Poland

ABC-Pulmo NZOZ Agnieszka Dobielska, Jaroslaw Dobie

Radom, 26-600, Poland

Centrum Medyczne KARDIOTEL

Sopot, 81-741, Poland

Kiepury Clinic

Sosnowiec, 41-200, Poland

Gabinet Pulmonologii i Diagnostyki Chorob Alergicznych Dorota Malosek

Szczecin, 70-111, Poland

NZOZ Poradnia Chorob Pluc i Alergologii

Słupsk, 76-200, Poland

Viltis Medica Specjalistyczna Praktyka Lekarska Lek. Med. Agata Kot

Trzebnica, 55-100, Poland

AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Warszawie

Warsaw, 01-192, Poland

Synexus Polska Sp. z o.o. Oddzial we Wroclawiu

Wroc?aw, 50-381, Poland

Centrum Badan Klinicznych Piotr Napora Lekarze Spolka Partnerska

Wroc?aw, 51-162, Poland

Lekarze Specjalisci J. Malolepszy i Partnerzy

Wroc?aw, 54-239, Poland

Medical Center Clinhouse

Zabrze, 41-807, Poland

Allianze Pulmonary Research LLC

Guaynabo, 00968, Puerto Rico

Iatros International

Bloemfontein, Free State 9301, South Africa

Newtown Clinical Research Centre

City of Johannesburg, Gauteng Hillbrow 2001, South Africa

Johese Clinical Research

Centurion, 1692, South Africa

Dr. Ismail Abdullah Private Practice

City of Cape Town, 7764, South Africa

CLINRESCO, ARWYP Medical Suites

Kempton Park, 1619, South Africa

AES - DRS - Synexus Watermeyer Clinical Research Centre

Pretoria, 0184, South Africa

Medicross Pretoria West, Jongaie Research

Pretoria, 183, South Africa

AES - DRS - Synexus - Helderberg Clinical Research Centre

Somerset West, 7130, South Africa

Dr Yacoob AK Private Practice

Welkom, 9459, South Africa

Soon Chun Hyang University Hospital Bucheon

Bucheon-si, 420-767, South Korea

Yeungnam University Hospital

Daegu, 42415, South Korea

CHA Bundang Medical Center

Gyeonggi-do, 13496, South Korea

Kangbuk Samsung Hospital

Seoul, 03181, South Korea

Asan Medical Center - PPDS

Seoul, 05505, South Korea

Samsung Medical Center - PPDS

Seoul, 06351, South Korea

Chung-Ang University Hospital

Seoul, 06973, South Korea

The Catholic University of Korea, Seoul St. Mary's Hospital

Seoul, 137-701, South Korea

Yonsei University Wonju Severance Christian Hospital

Wŏnju, 220-701, South Korea

Hospital Universitario Son Espases

Palma de Mallorca, Balearic Islands 07010, Spain

Hospital El Bierzo

Ponferrada, LEON 24411, Spain

Hospital Universitario de Torrejon

Torrejón de Ardoz, Madrid 28850, Spain

Vithas Xanit International Hospital

Benalmádena Costa, Malaga 29630, Spain

Hospital Universitario La Paz - PPDS

Barcelona, 8041, Spain

Hospital Universitario Virgen del Rocio

Seville, 41013, Spain

Hospital Clinico Universitario de Valencia

Valencia, 46010, Spain

Hospital de La Ribera

Valencia, 46600, Spain

Clinical Trial Consultants - Linkoping

Uppsala, Uppsala County 752 37, Sweden

Sahlgrenska Universitetssjukhuset

Gothenburg, 413 45, Sweden

Akardo AB

Stockholm, 117 27, Sweden

Zurcher Reha Zentren Wald

Zurich, Switzerland

Changhua Christian Hospital

Chang-hua, 500, Taiwan

Kaohsiung Medical University Hospital

Kaoshiung City, 807, Taiwan

Far East Memorial Hospital

New Taipei City, 220, Taiwan

Taipei Medical University Hospital

Taipei, 11031, Taiwan

Taipei Veterans General Hospital

Taipei, 11217, Taiwan

Tri-Service General Hospital

Taipei, 11490, Taiwan

Srinagarind Hospital, Khon Kaen University

Khon Kaen, 40002, Thailand

Central Chest Institute of Thailand

Muang, 11000, Thailand

Kirikkale Universitesi Tip Fakultesi Hastanesi

Kirikkale, 71100, Turkey (Türkiye)

Rize Recep Tayyip Erdogan University Training and Research Hospital

Rize Merkez, 53020, Turkey (Türkiye)

Cukurova Universitesi Tip Fakultesi Balcali Hastanesi

Sarıçam, 01250, Turkey (Türkiye)

Castle Hill Hospital

Cottingham, Yorkshire HU16 5JQ, United Kingdom

AES - DRS - Synexus Scotland Clinical Research Centre

Bellshill, ML4 3NJ, United Kingdom

AES - DRS - Synexus Midlands Clinical Research Centre

Birmingham, B15 2SQ, United Kingdom

AES - DRS - Synexus Wales Clinical Research Centre

Cardiff, CF15 9SS, United Kingdom

Royal Primary Care - Ashgate Manor

Chesterfield, S40 4AA, United Kingdom

AES - DRS - NW Consortium Lancashire

Chorley, PR7 7NA, United Kingdom

Royal Infirmary of Edinburgh

Edinburgh, EH16 4SA, United Kingdom

AES - DRS - Synexus Hexham Clinical Research Centre

Hexham, NE46 1QJ, United Kingdom

Royal Lancaster Infirmary

Lancaster, LA1 4RP, United Kingdom

St James University Hospital

Leeds, LS9 7TF, United Kingdom

AES - DRS - NW Consortium Merseyside

Liverpool, L32 2AN, United Kingdom

Velocity Clinical Research North London - Percy Road - PPDS

London, N12 8BU, United Kingdom

St Thomas' Hospital

London, SE1 7EH, United Kingdom