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the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.
Patients and methods:
Type of study: Observational prospective study
Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit.
Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients.
Study Methods:
A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge.
All patients included in the study will be subjected to:
Full history:
Detailed clinical examination
Electrocardiogram
Laboratory investigation:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| (CBC) ,(NT-proBNP) ,(cTnT) | Diagnostic Test | complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients. |
| Measure | Description | Time Frame |
|---|---|---|
| (CBC) | measurement of CBC will be performed at the time of admission and by the time of discharge. | 6 months |
| (NT-proBNP | measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge. | 6 months |
| (cTnT) | measurement of cTnT levels will be performed at the time of admission and by the time of discharge | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
Patient with:
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• All patients included in the study will be subjected to:
Full history:
Detailed clinical examination
Electrocardiogram
Laboratory investigation:
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hemat k Maarouf, resident doctor | Contact | 01063296647 | hemat011219@med.sohag.edu.eg | |
| Abdelhady R Abdel-Gawad, assistant professor | Contact |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag University Hospital | Sohag | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30269080 | Background | Nascimento BR, Brant LCC, Marino BCA, Passaglia LG, Ribeiro ALP. Implementing myocardial infarction systems of care in low/middle-income countries. Heart. 2019 Jan;105(1):20-26. doi: 10.1136/heartjnl-2018-313398. Epub 2018 Sep 29. | |
| 30269044 | Background | Barberi C, van den Hondel KE. The use of cardiac troponin T (cTnT) in the postmortem diagnosis of acute myocardial infarction and sudden cardiac death: A systematic review. Forensic Sci Int. 2018 Nov;292:27-38. doi: 10.1016/j.forsciint.2018.09.002. Epub 2018 Sep 17. |
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| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| ID | Term |
|---|---|
| D001772 | Blood Cell Count |
| ID | Term |
|---|---|
| D002452 | Cell Count |
| D003584 | Cytological Techniques |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
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| 30265127 | Background | Alaour B, Liew F, Kaier TE. Cardiac Troponin - diagnostic problems and impact on cardiovascular disease. Ann Med. 2018 Dec;50(8):655-665. doi: 10.1080/07853890.2018.1530450. Epub 2018 Nov 21. |
| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D003933 | Diagnosis |
| D006403 | Hematologic Tests |
| D008919 | Investigative Techniques |
| D002468 | Cell Physiological Phenomena |
| D001790 | Blood Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |