Neural Bases of Post-stroke Emotion Perception Disorders

Neural Bases of Post-stroke Emotion Perception Disorders

This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.

This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs healthy controls (2 groups of 40 subjects). It will include functional MRI, structural MRI (disconnectome), EEG, and behavioral assessments of emotion recognition and executive functions.

Inclusion Criteria:

Stroke group:

• Man or Woman
• Age 18-80y
• Unique stroke, ischemic or hemorrhagic
• at the chronic phase (< 6 months)
• Written informed consent
• subject having a social insurance
• Subject who consent to complete all the study's experiments

Healthy controls group:

• Man or Woman
• Age 18-80y
• No history of neurological or psychiatric disease.

Exclusion Criteria:

Stroke group

• Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
• History of other neurologic disorders
• Significant le vel of depression or anxiety, assessed by the STAI and the BDI questionnaires
• Non corrected visual loss
• Subjects suffering from visual neglect (assessed by the Bells Test and a bisection test (20mm)
• contra-indications to MRI
• pregnant or breastfeeding woman
• Women of childbearing age without effective contraception

Healthy controls group

• Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
• History of neurologic disorders
• Significant level of depression or anxiety, assessed by the STAI and the BDI questionnaires
• Non-corrected visual loss
• contra-indications to MRI
• pregnant or breastfeeding woman
• Women of childbearing age without effective contraception