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Hybrid closed-loop technology have shown that it improves glycemic control parameters, but the investigators do not have sufficient data at more than 6 months of follow-up, allowing us to describe the effectiveness of these systems in the long term.
All MiniMed 780G system users from November 2020 to March 2022 were included (n=32) For every time points, there was a significant difference in Time In Range between the pre-AHCL and post-AHCL. Noted difference were +14.5% and, +10.8% at respectively 3 months and 1 year. No more hypoglycemia were identified.
This "real-life" analysis shows that the algorithm is effective in improvement of metabolic control for T1 diabetic children and adolescents, at one year of follow-up.
However, an effect of breathlessness is observed which underlined the need for a solid therapeutic education program.
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| Measure | Description | Time Frame |
|---|---|---|
| Glycated hemoglobin | Percentage of glycated hemoglobin measured by the MiniMed 780G system | 1 year |
| Time spent in range Level with glucose levels within the norm | Time spent with glucose levels between 70 and 180 mg/dL | 1 year |
| Time spent with glucose levels below range | Time spent with glucose levels inferior to 70mg/dL | 1 year |
| Time spent with glucose levels above range | Time spent with glucose levels superior to 180 mg/dL | 1 year |
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Inclusion criteria:
All children with type 1 diabetes in whom a Medtronic G780 closed-loop pump was placed between November 2020 and March 2022 in our center were included.
Exclusion criteria:
Participant opposition
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Diabetic minors treated with closed-loop insulin pumps
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| Name | Affiliation | Role |
|---|---|---|
| Fabienne Dalla Vale, PH | University Hospital, Montpellier | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Uhmontpellier | Montpellier | 34295 | France |
NC
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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