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| Name | Class |
|---|---|
| Centro Superior de Estudios Universitarios Lasalle | UNKNOWN |
| King's College London | OTHER |
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Study with the aim to see the effect on a space ground analogue , Hyper-Buoyancy Floatation (HBF) on lumbar column and the effect of a supplementary 50% of an axial load.
the aim of this study was to determine the effect of 15min of 1g reloading following 4h HBF unloading with, and without 30s of seated static 50% BW axial loading upon stature, lumbar Intervertebral Disc height (via ultrasound), vertebral compliance changes, and back pain.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental Group | 8 participants (4 males, 25.5±4.4 years, 63.5±10.6 kg, 163.2±5.6 cm) |
| |
| Observational Group | 8 participants (3 males, 27.0±2.0 years, 68.4±11.8 kg, 176.5±10.9 cm |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hyper-buoyancy Floatation (HBF) | Device | Participants remained on a waterbed encased within a wooden frame partially (≈50%) filled with water super-saturated with magnesium sulphate at a temperature between 34-36°C regulated by an ultra-thin underbed heater. Participants remained supine and motionless when lay on the HBF except for temporary passive re-orientation to/and back from the prone position for vertebral compliance assessment |
| Measure | Description | Time Frame |
|---|---|---|
| Height | Standing stature measured by a commercial stadiometer (Seca 217, Germany) | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Intervertebral Disc Height | Disc height (L2-S1) measured by ultrasound | 2 years |
| Vertebral Stiffness | Vertebral stiffness from L1 to L5 was assessed passively (in the prone position) with a handheld differential vertebral compliance transducer (PulStar, Sense Technology Inc., USA) in Newtons. |
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Inclusion Criteria:
Exclusion Criteria:
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NASA astronaut criteria (1.57-1.90m, 50-95kg)
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| Name | Affiliation | Role |
|---|---|---|
| David Green, PhD | King's College London | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad Autónoma de Madrid | Madrid | 28023 | Spain | |||
| King's College London |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32982803 | Background | Swanenburg J, Langenfeld A, Easthope CA, Meier ML, Ullrich O, Schweinhardt P. Microgravity and Hypergravity Induced by Parabolic Flight Differently Affect Lumbar Spinal Stiffness. Front Physiol. 2020 Sep 2;11:562557. doi: 10.3389/fphys.2020.562557. eCollection 2020. | |
| 29403389 | Result | Green DA, Scott JPR. Spinal Health during Unloading and Reloading Associated with Spaceflight. Front Physiol. 2018 Jan 18;8:1126. doi: 10.3389/fphys.2017.01126. eCollection 2017. |
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Data is going to be shared between the investigators authors
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|
| Axial Load after 4h of HBF | Device | Participants from observational sat upright in a chair without back support for 15 min before post testing (1G), whilst experimental group participants performed a 30s seated squat with 50% of their body weight (BW) before returning to the upright seated position. |
|
| 2 years |
| Self-reported back pain | Pain rating scale (CHAPS) from 0 to 10 | 2 years |
| London |
| SE1 1UL |
| United Kingdom |
| 24135505 | Result | Marshburn TH, Hadfield CA, Sargsyan AE, Garcia K, Ebert D, Dulchavsky SA. New heights in ultrasound: first report of spinal ultrasound from the international space station. J Emerg Med. 2014 Jan;46(1):61-70. doi: 10.1016/j.jemermed.2013.08.001. Epub 2013 Oct 15. |
| 27779600 | Result | Chang DG, Healey RM, Snyder AJ, Sayson JV, Macias BR, Coughlin DG, Bailey JF, Parazynski SE, Lotz JC, Hargens AR. Lumbar Spine Paraspinal Muscle and Intervertebral Disc Height Changes in Astronauts After Long-Duration Spaceflight on the International Space Station. Spine (Phila Pa 1976). 2016 Dec 15;41(24):1917-1924. doi: 10.1097/BRS.0000000000001873. |
| ID | Term |
|---|---|
| D009133 | Muscular Atrophy |
| D013124 | Spinal Injuries |
| ID | Term |
|---|---|
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D019567 | Back Injuries |
| D014947 | Wounds and Injuries |
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