Comparing SBRT to CRT in Patients With Spinal Metastases

Prospective Registry Trail COMparing Stereotactic Body Radiotherpy (SBRT) to Conventional PAlliative RadioTherapy (CRT) in Patients With Spinal Metastases

This is a single institutional registry-based, prospective, observational study to describe radiation oncologists' decision making during evaluation of patients and to compare real-world outcomes of SBRT vs CRT.

A registry-based trial involves observing the effect of something without manipulating it.

The purpose of this study is to study the differences between CRT and SBRT. The investigator's are assessing radiation oncologists' decision-making during the evaluation of patients with spinal metastases by requesting radiation oncologists complete a questionnaire. Additionally, the investigator's will compare outcomes, including local progression, pain response and overall survival between SBRT and CRT. By collecting this information, the investigator's will develop an evidence-based algorithm that may be used to support medical decision-making for others with spinal metastases in the future.

Inclusion Criteria:

• Adults 18 years of age or older.
• Patients seen at the Princess Margaret Cancer Centre with painful spinal metastases amenable to radiation treatment.
• Confirmation of diagnosis: a) Known/documented prior histological cancer diagnosis
• Able to provide written consent
• ECOG performance status 0-3

Exclusion Criteria:

• Prior radiotherapy, with fields overlapping, resulting in excessive doses to organs at risk
• Lymphoma, myeloma or germ cell malignancies