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This goal of this clinical study is to investigate the postprandial glycemic and insulinemic response in healthy adults after the consumption of:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Glucose - Control | Active Comparator | 20 g of glucose mixed with 250 ml of cold water |
|
| SFF | Experimental | 20 g of SFF mixed with 250 ml of cold water |
|
| Regular chocolate chips - Control | Active Comparator | 50 g of regular chocolate chips |
|
| SFF chocolate chips | Experimental | 50 g of SFF chocolate chips |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SFF | Dietary Supplement | Ingestion of 20g of SFF after 10-14 hours of fasting |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma glucose iAUC (T0 - T120min) after test meals | Compare the postprandial glucose incremental area under the curve after consumption of: SFF compared to glucose or SFF chocolate chips compared to regular chocolate chips | Through intervention periods of two hours |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma glucose at each time point after test meals | Compare the postprandial glucose levels at each time point after consumption of: SFF compared to glucose or SFF chocolate chips compared to regular chocolate chips | Through intervention periods of two hours |
| Serum insulin iAUC (T0 - T120min) and each time point after test meals |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thomas Wolever, Ph.D | INQUIS Clinical Research | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| INQUIS Clinical Research, Ltd | Toronto | Ontario | M5C 2N8 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38032277 | Derived | Moura de Oliveira Beltrame D, Simmons TJ, Jenkins AL, Dinan T, Nicholson TJ. Gastrointestinal Tolerability and Acute Glycemic Response of Oligosaccharides and Polysaccharides from Cellulose and Xylan in Healthy Adults: Two Double-Blinded, Randomized, Controlled, Cross-over Trials. J Am Nutr Assoc. 2024 May-Jun;43(4):305-314. doi: 10.1080/27697061.2023.2282615. Epub 2023 Nov 30. |
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| ID | Term |
|---|---|
| D005947 | Glucose |
| ID | Term |
|---|---|
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |
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| Glucose |
| Dietary Supplement |
Ingestion of 20g of glucose after 10-14 hours of fasting |
|
| SFF chocolate chips | Dietary Supplement | Ingestion of 50g of chocolate chips made with SFF after 10-14 hours of fasting |
|
| Regular chocolate chips | Dietary Supplement | Ingestion of 50g of regular chocolate chips after 10-14 hours of fasting |
|
Compare the postprandial insulin levels at each time and incremental area under the curve after consumption of: SFF compared to glucose or SFF chocolate chips compared to regular chocolate chips |
| Through intervention periods of two hours |