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Punctal stenosis is a progressive constriction of the puncta with resultant epiphora. One of the most effective treatment options is 1- to 4-snip punctoplasty combined with or without Mitomycin-C.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 3-snip punctoplasty | Active Comparator |
| |
| 3-snip punctoplasty with mitomycin C | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 3-snip punctoplasty | Procedure | punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease. |
| Measure | Description | Time Frame |
|---|---|---|
| Punctal patency | Punctum will be assessed by inspection of the lid by slitlamb examination, whither obstructed or not | Baseline |
| Punctal patency | Punctum will be assessed by inspection of the lid by slitlamb examination, whither obstructed or not | 1 week postoperative |
| Punctal patency | Punctum will be assessed by inspection of the lid by slitlamb examination, whither obstructed or not | 1 month postoperative |
| Punctal patency | Punctum will be assessed by inspection of the lid by slitlamb examination, whither obstructed or not | 3 months postoperative |
| Presence of Epiphora | It will be assessed by inspection of the lid by slitlamb examination. | Baseline |
| Presence of Epiphora | It will be assessed by inspection of the lid by slitlamb examination. | 1 week postoperative |
| Presence of Epiphora | It will be assessed by inspection of the lid by slitlamb examination. | 1 month postoperative |
| Presence of Epiphora | It will be assessed by inspection of the lid by slitlamb examination. |
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Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ehab tharwat | Damietta | New Damietta | 34517 | Egypt |
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| ID | Term |
|---|---|
| D016685 | Mitomycin |
| ID | Term |
|---|---|
| D008937 | Mitomycins |
| D045563 | Indolequinones |
| D011809 | Quinones |
| D009930 | Organic Chemicals |
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|
| 3-snip punctoplasty and Mitomycin C | Procedure | punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease. Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis |
|
| 3 month postoperative |
| D001389 |
| Azirines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D007211 | Indoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |