Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Quorn | INDUSTRY |
Not provided
Not provided
Not provided
Not provided
The bulk of research that has investigated the effect of dietary protein on muscle tissue in humans has used isolated, minimally processed protein powders. However, the protein that we consume on a daily basis has typically undergone various processing methods, and evidence suggests these can change the way our bodies metabolise the protein. 'Extrusion' is a common processing method that uses high pressure to produce protein containing cereals and meat replacement foods. There is currently no research looking at how extrusion affects the way a protein source is digested and absorbed in humans. This study will compare the availability of ingested protein in the blood in the hours following consumption of an extruded versus a non-extruded source.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dry Blend | Experimental | A dry blend of mycoprotein and pea protein. |
|
| Extrudate | Experimental | An extruded blend of mycoprotein and pea protein |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dry protein blend ingestion | Dietary Supplement | Ingestion of protein blend powders mixed in water |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasma amino acid concentrations | The rate of appearance of amino acids ingested in the drink | 5 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Blood glucose | The concentrations of glucose in the blood | 5 hours |
| Serum insulin | The concentration of insulin in the blood | 5 hours |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Benjamin Wall | Professor of Nutritional Physiology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sport & Health Sciences University of Exeter | Exeter | Devon | EX1 2LU | United Kingdom | ||
| University of Exeter |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38797481 | Derived | West S, Monteyne AJ, Whelehan G, Abdelrahman DR, Murton AJ, Finnigan TJ, Mandalari G, Booth C, Wilde PJ, Stephens FB, Wall BT. High-Moisture Extrusion of a Dietary Protein Blend Impairs In Vitro Digestion and Delays In Vivo Postprandial Plasma Amino Acid Availability in Humans. J Nutr. 2024 Jul;154(7):2053-2064. doi: 10.1016/j.tjnut.2024.05.018. Epub 2024 May 24. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Extruded protein blend ingestion | Dietary Supplement | Ingestion of protein blend powders mixed in water |
|
| Resting metabolic rate | The amount of energy used to digest the protein | 5 hours |
| Exeter |
| Devon |
| EX1 2LU |
| United Kingdom |