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The retrospective cohort study will compare the prevalence of sarcopenia and associated factors between older patients who have undergone bariatric surgery and older patients with obesity without previous bariatric surgery.
The aim of the study is to compare the prevalence of sarcopenia and nutritional status between adults older than 65 years who have previously undergone bariatric surgery and patients with obesity but without previous bariatric surgery. Current sarcopenia will be assessed during a cross-sectional assessment after surgery using the criteria from the European Working Group on Sarcopenia in Older People (EWGSOP).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cohort 1 | Cohort 1: Older patients with overweight, obesity after bariatric surgery |
| |
| Cohort 2 | Cohort 2: Older patients with overweight, obesity without bariatric surgery |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bariatric surgery | Procedure | Bariatric surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| The number of older patients with sarcopenia after bariatric surgery compared to non-surgical control patients. | a) Sarcopenia will be classified according to the criteria form the European Working Group on Sarcopenia in Older People revised guidelines (EWGSOP2) based on skeletal muscle mass, muscle strength and physical performance criteria. | At least one year post surgery |
| Measure | Description | Time Frame |
|---|---|---|
| 1. Appendicular skeletal muscle mass older of patients after bariatric surgery compared to non-surgical control patients | 1. Appendicular skeletal muscle mass older of patients after bariatric surgery compared to non-surgical control patients | At least one year post surgery |
| 2. The prevalence of nutrient deficiencies in older patients after bariatric surgery compared to non-surgical control patients. |
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Inclusion Criteria:
Exclusion Criteria:
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Subjects with overweight, obesity or after bariatric surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Obesity Clinic University Hospitals Leuven | Leuven | 3000 | Belgium |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40468919 | Derived | Eksteen G, Vanuytsel T, Vangoitsenhoven R, Mertens A, Lannoo M, De Leus E, Van der Schueren B, Matthys C. Sarcopenia, Muscle Mass and Protein Intake in Adults Older Than 65 Years After Earlier Bariatric Surgery. J Cachexia Sarcopenia Muscle. 2025 Jun;16(3):e13839. doi: 10.1002/jcsm.13839. |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| ID | Term |
|---|---|
| D050110 | Bariatric Surgery |
| ID | Term |
|---|---|
| D049088 | Bariatrics |
| D000073319 | Obesity Management |
| D013812 | Therapeutics |
| D013514 | Surgical Procedures, Operative |
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a. Indices of nutrient deficiencies will include reported dietary intake of protein, zinc, selenium, and blood levels of Vitamin D, zinc, and selenium. |
| At least one year post surgery |
| 3. Markers of chronic systemic inflammation in older patients after bariatric surgery compared to non-surgical control patients | Inflammatory markers will include CRP, IL-1β, IL-6, IL-8, TNF-α | At least one year post surgery |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |