Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This prospective study aims to perform intra-individual comparison of the image quality between ultra-low-dose whole-body CT with deep learning reconstruction and conventional low-dose whole-body CT with iterative reconstruction in patients with suspected multiple myeloma.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Multiple myeloma | Patients with suspicion of multiple myeloma and scheduled for CT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| noncontrast-enhanced whole-body CT | Diagnostic Test | noncontrast-enhanced low-dose whole-body CT using dual-source CT scanner using A-tube (75% radiation) and B-tube (25% radiation).
|
| Measure | Description | Time Frame |
|---|---|---|
| Contrast-to-noise ratio | Contrast-to-noise ratio (CNR) of the vertebral body and paraspinal muscle obtained at L1 vertebra level | 3 months after the CT scan |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Noise | Noise at paraspinal muscle | 3 months after the CT scan |
| Signal-to-noise ratio (SNR) | Signal-to-noise ratio (SNR) at paraspinal muscle |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Patients who are referred to Hemoatooncology department with suspicion of multiple myeloma
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hee-Dong Chae, MD | Contact | 82-2-2072-4209 | hdchae02@gmail.com | |
| Jeong Hoon Park, BS | Contact | 82-2-2072-3610 | gns02066@naver.com |
| Name | Affiliation | Role |
|---|---|---|
| Hee-Dong Chae, MD | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Recruiting | Seoul | 03080 | South Korea |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D009101 | Multiple Myeloma |
| ID | Term |
|---|---|
| D054219 | Neoplasms, Plasma Cell |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D020141 | Hemostatic Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| 3 months after the CT scan |
| Edge rising distance | Edge rising distance at vertebral cortex | 3 months after the CT scan |
| Subjective overall image quality | Subjective overall image quality on four-point scale (1: worst, 4: excellent, representative value is average score) | 3 months after the CT scan |
| Conspicuity of bone structure | Conspicuity of bone structure on four-point scale (1: worst, 4: excellent, representative value is average score) | 3 months after the CT scan |
| Conspicuity of soft tissue | Conspicuity of soft tissue on four-point scale (1: worst, 4: excellent, representative value is average score) | 3 months after the CT scan |
| Lesion detectability | Myeloma lesion detection rate on conventional low-dose CT and ultra-low-dose CT by blinded reviewers | 3 months after the CT scan |
| D014652 |
| Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010265 | Paraproteinemias |
| D001796 | Blood Protein Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006474 | Hemorrhagic Disorders |
| D008232 | Lymphoproliferative Disorders |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |