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Advances in medicine have led to an increased life expectancy even with complex disease courses of malignant diseases.
This leads to frequent critical situations for patients and high risk surgical interventions. The majority of patients and their practitioners are not prepared for the consequences of a complex and possibly fatal course.
Palliative medicine makes it possible to anticipate the further course of the disease. As a result, palliative medicine has become increasingly important. The beginning of palliative medical interventions has extended from accompaniment limited to the dying phase to earlier phases of the disease.
An early integration of palliative medicine showed a positive effect on the quality of life, the degree of depression and survival in patients suffering from cancer, for example. Furthermore, patients were more able to accept a change in therapy goal at the end of life. Similar results were shown for patients with a non-malignant severe disease such as COPD or heart failure.
What needs further investigating is how to adequately screen and identify the patient populations who could benefit from early palliative care, so that they are prepared for potentially critical and life-threatening situations.
The investigator's objective is therefore whether the Anesthesiology Outpatient Clinic is a suitable screening location for initiating early integrated palliative care for patients with a serious, life-shortening illness and a high perioperative risk.
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| Measure | Description | Time Frame |
|---|---|---|
| Acceptance of the preoperative palliative counseling offer | Percentage of patients who accept the palliative counseling offer in relation to the total number of patients identified in the screening of the anesthesia outpatient clinic | through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Advance planning documents | Percentage of patients who, as a result of the palliative medical consultation offer, create or want to create a living will or power of attorney | through study completion, an average of 1 year |
| Postoperative palliative counseling |
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Inclusion Criteria:
And in addition at least one of the following criteria:
Exclusion Criteria:
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The participants will be selected out of the population consulted at the anesthesiology outpatient clinic of the University hospital Berlin - Charite.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesia and operative intensive Care, Campus Benjamin Franklin, Charité - University Hospital Berlin | Recruiting | Steglitz | State of Berlin | 12203 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20818875 | Background | Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, Dahlin CM, Blinderman CD, Jacobsen J, Pirl WF, Billings JA, Lynch TJ. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010 Aug 19;363(8):733-42. doi: 10.1056/NEJMoa1000678. | |
| 29402701 | Background |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D006333 | Heart Failure |
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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Percentage of patients who would like further palliative medical advice postoperatively |
| through study completion, an average of 1 year |
| Acceptance of the preoperative palliative counseling offer depending on the underlying disease | Percentage of patients with and without a malignant disease who accept the counseling offer | through study completion, an average of 1 year |
| Therapy target decision-making situations | Percentage of patients in whom a decision to limit therapy occurs in the postoperative course | through study completion, an average of 1 year |
| Gender difference | Percentage of female patients who accept the counseling offer in relation to male patients | through study completion, an average of 1 year |
| Therapy goal decisions postoperatively | Percentage of patients who do not accept the offer of counseling and who have difficult therapy goal decisions postoperatively | through study completion, an average of 1 year |
| Vanbutsele G, Pardon K, Van Belle S, Surmont V, De Laat M, Colman R, Eecloo K, Cocquyt V, Geboes K, Deliens L. Effect of early and systematic integration of palliative care in patients with advanced cancer: a randomised controlled trial. Lancet Oncol. 2018 Mar;19(3):394-404. doi: 10.1016/S1470-2045(18)30060-3. Epub 2018 Feb 3. |
| 31812934 | Background | Vanbutsele G, Van Belle S, Surmont V, De Laat M, Colman R, Eecloo K, Naert E, De Man M, Geboes K, Deliens L, Pardon K. The effect of early and systematic integration of palliative care in oncology on quality of life and health care use near the end of life: A randomised controlled trial. Eur J Cancer. 2020 Jan;124:186-193. doi: 10.1016/j.ejca.2019.11.009. Epub 2019 Dec 5. |
| 27472648 | Background | Maltoni M, Scarpi E, Dall'Agata M, Zagonel V, Berte R, Ferrari D, Broglia CM, Bortolussi R, Trentin L, Valgiusti M, Pini S, Farolfi A, Casadei Gardini A, Nanni O, Amadori D; Early Palliative Care Italian Study Group (EPCISG). Systematic versus on-demand early palliative care: results from a multicentre, randomised clinical trial. Eur J Cancer. 2016 Sep;65:61-8. doi: 10.1016/j.ejca.2016.06.007. Epub 2016 Jul 26. |
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| 17608870 | Background | Brumley R, Enguidanos S, Jamison P, Seitz R, Morgenstern N, Saito S, McIlwane J, Hillary K, Gonzalez J. Increased satisfaction with care and lower costs: results of a randomized trial of in-home palliative care. J Am Geriatr Soc. 2007 Jul;55(7):993-1000. doi: 10.1111/j.1532-5415.2007.01234.x. |
| 31609772 | Background | Ma J, Chi S, Buettner B, Pollard K, Muir M, Kolekar C, Al-Hammadi N, Chen L, Kollef M, Dans M. Early Palliative Care Consultation in the Medical ICU: A Cluster Randomized Crossover Trial. Crit Care Med. 2019 Dec;47(12):1707-1715. doi: 10.1097/CCM.0000000000004016. |
| 31895424 | Background | Yefimova M, Aslakson RA, Yang L, Garcia A, Boothroyd D, Gale RC, Giannitrapani K, Morris AM, Johanning JM, Shreve S, Wachterman MW, Lorenz KA. Palliative Care and End-of-Life Outcomes Following High-risk Surgery. JAMA Surg. 2020 Feb 1;155(2):138-146. doi: 10.1001/jamasurg.2019.5083. |
| 24716263 | Background | Cancer Control: Knowledge into Action: WHO Guide for Effective Programmes: Module 5: Palliative Care. Geneva: World Health Organization; 2007. Available from http://www.ncbi.nlm.nih.gov/books/NBK195248/ |
| 34924178 | Background | Chan R, Ueno R, Afroz A, Billah B, Tiruvoipati R, Subramaniam A. Association between frailty and clinical outcomes in surgical patients admitted to intensive care units: a systematic review and meta-analysis. Br J Anaesth. 2022 Feb;128(2):258-271. doi: 10.1016/j.bja.2021.11.018. Epub 2021 Dec 17. |
| 29156482 | Background | Morgeli R, Wollersheim T, Spies C, Balzer F, Koch S, Treskatsch S. [How to Reduce the Rate of Postoperative Complications in Frail Patients?]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2017 Nov;52(11-12):785-797. doi: 10.1055/s-0043-104685. Epub 2017 Nov 20. German. |
| 29156481 | Background | Birkelbach O, Morgeli R, Balzer F, Olbert M, Treskatsch S, Kiefmann R, Muller-Werdan U, Reisshauer A, Schwedtke C, Neuner B, Spies C. [Why and How Should I Assess Frailty? A Guide for the Preoperative Anesthesia Clinic]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2017 Nov;52(11-12):765-776. doi: 10.1055/s-0043-104682. Epub 2017 Nov 20. German. |
| 31699033 | Background | Birkelbach O, Morgeli R, Spies C, Olbert M, Weiss B, Brauner M, Neuner B, Francis RCE, Treskatsch S, Balzer F. Routine frailty assessment predicts postoperative complications in elderly patients across surgical disciplines - a retrospective observational study. BMC Anesthesiol. 2019 Nov 7;19(1):204. doi: 10.1186/s12871-019-0880-x. |
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| 22374658 | Background | Schoffner M, Schmidt KW, Benzenhofer U, Sahm S. [Living wills under close scrutiny: Medical consultation is indispensable]. Dtsch Med Wochenschr. 2012 Mar;137(10):487-90. doi: 10.1055/s-0031-1298998. Epub 2012 Feb 28. German. |
| 25139124 | Background | Pfirstinger J, Kattner D, Edinger M, Andreesen R, Vogelhuber M. The impact of a tumor diagnosis on patients' attitudes toward advance directives. Oncology. 2014;87(4):246-56. doi: 10.1159/000363508. Epub 2014 Aug 15. |
| 30883399 | Background | Urman RD, Gross CS, Sadovnikoff N, Bader AM. Improving Preoperative Completion of Advanced Care Planning Documents in Patients With Expected Postoperative Intensive Care Unit Stay. A A Pract. 2019 Jun 15;12(11):455-458. doi: 10.1213/XAA.0000000000000993. |
| 34550339 | Background | Hadler RA, Fatuzzo M, Sahota G, Neuman MD. Perioperative Management of Do-Not-Resuscitate Orders at a Large Academic Health System. JAMA Surg. 2021 Dec 1;156(12):1175-1177. doi: 10.1001/jamasurg.2021.4135. |
| 32311465 | Background | Scally CP, Robinson K, Blumenthaler AN, Bruera E, Badgwell BD. Identifying Core Principles of Palliative Care Consultation in Surgical Patients and Potential Knowledge Gaps for Surgeons. J Am Coll Surg. 2020 Jul;231(1):179-185. doi: 10.1016/j.jamcollsurg.2020.03.036. Epub 2020 Apr 18. |
| D012140 |
| Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |