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| ID | Type | Description | Link |
|---|---|---|---|
| 11/LO/1889 | Other Identifier | NRES |
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| Name | Class |
|---|---|
| GOSHCC | UNKNOWN |
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Walking measurement in children is important but there are challenges associated with obtaining reliable repeatable data in a clinical setting that is meaningful and easy to interpret. This study set out to develop a new way to collect, record, and interpret walking data that is suitable for the clinical environment. Developmental percentile charts were selected as they are widely recognised and easily interpreted.
The primary output of the main cohort of typically developing children is the developmental percentile charts.
These will be then used to present the clinical longitudinal data against a normal backdrop of developmental changes in children.
This has multiple clinical applications in many of the children assessed by physiotherapy at GOSH and more widely Nationally and internationally
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Typically developing children | Active Comparator | 500 children aged 1-18 male and female will be recruited from local schools, after school clubs and playgroups. Each child will complete a screening form following appropriate information and consent process. Each child will then complete the walking assessment which takes 15 minutes in total |
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| Clinical groups | Active Comparator | Children will be recruited through their patient journey. Families who consent to participation will complete the screening form and the GAITRite walking assessment as part of their pre-planned clinical followup in outpatient clinics. One group of children will be assessed at one time point, whilst a second group of children with progressive orthopaedic conditions or treatment will be assessed at intervals to give longitudinal data |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gait assessment using the GAITRIte walkway | Device | 10-20 walking assessment using the GAITRite walkway |
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| Measure | Description | Time Frame |
|---|---|---|
| Gait data recorded via GAITRite software | Continuous numeric data summarising walking performance and characteristics | For the duration of the study measured once for typically developing and at multiple clinic visits over 24 months for clinical groups |
| Measure | Description | Time Frame |
|---|---|---|
| demographic and clinical outcome data | surgical history (where relevant) | 30 to 60 mins to collect relevant data at a single time point, with an update to include additional admissions over 24months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lucy Alderson, PhD | Great Ormond Street Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Great Ormond Street Hospital | London | WC1N 3JH | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19319660 | Background | Wood M, Cleary MA, Alderson L, Vellodi A. Changes in gait pattern as assessed by the GAITRite walkway system in MPS II patients undergoing enzyme replacement therapy. J Inherit Metab Dis. 2009 Dec;32 Suppl 1:S127-35. doi: 10.1007/s10545-009-1103-2. Epub 2009 Mar 25. | |
| 17880441 | Background | Bladen M, Alderson L, Khair K, Liesner R, Green J, Main E. Can early subclinical gait changes in children with haemophilia be identified using the GAITRite walkway. Haemophilia. 2007 Sep;13(5):542-7. doi: 10.1111/j.1365-2516.2007.01429.x. |
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Only summary centile charts for norms will be available with no individual identifiers
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The tool used for this study has been and was used for routine patient care, but was a novel diagnostic assessment for the typically developing (norms) and some of the clinical groups included. The clinical groups were compared to norms, both had the same diagnostic assessment so there was no control group who did not have the assessment
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All children recruited underwent the GAITRite assessment
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| 30910816 | Result | Alderson LM, Joksaite SX, Kemp J, Main E, Watson T, Platt FM, Cortina-Borja M. Age-related gait standards for healthy children and young people: the GOS-ICH paediatric gait centiles. Arch Dis Child. 2019 Aug;104(8):755-760. doi: 10.1136/archdischild-2018-316311. Epub 2019 Mar 25. |