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| ID | Type | Description | Link |
|---|---|---|---|
| J1P-MC-KFAN | Other Identifier | Eli Lilly and Company |
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| Name | Class |
|---|---|
| Eli Lilly and Company | INDUSTRY |
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The purpose of this study is to compare two different formulations (test & reference) of LY3471851 in healthy participants. This study will compare how much of each formulation gets into the blood stream and how long it takes the body to remove it. Information about any side effects that may occur will also be collected. Participants will remain in the study for about 12 weeks, after receiving the study drug that is LY3471851.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LY3471851 (Test formulation) | Experimental | LY3471851 administered subcutaneously (SC). |
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| LY3471851 (Test) + Levocetirizine | Experimental | LY3471851 administered SC in combination with levocetirizine given orally. |
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| LY3471851 (Reference formulation) | Active Comparator | LY3471851 administered SC. |
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| Placebo | Placebo Comparator | Placebo administered SC. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| LY3471851 | Drug | Administered SC. |
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| Measure | Description | Time Frame |
|---|---|---|
| Pharmacokinetics (PK): Maximum Concentration (Cmax) of LY3471851 | PK: Cmax of LY3471851 | Predose up to 56 days postdose |
| PK: Area Under the Concentration Versus Time Curve (AUC) of LY3471851 | PK: AUC of LY3471851 | Predose up to 56 days postdose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Study Director | Nektar Therapeutics | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Covance Dallas | Dallas | Texas | 75247 | United States |
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| ID | Term |
|---|---|
| C472067 | levocetirizine |
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| Placebo | Drug | Administered SC. |
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| Levocetirizine | Drug | Administered orally. |
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