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This study aims to compare choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia.
All patients will be examined by optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-angio) .
The size, the location, the criteria of the choriodal neovascular membrane will be examined and imaged.
Study include 50 cases of CNV in age related macular degeneration and 50 cases of CNV in pathological myopia.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with age related macular degeneration with CNV |
| ||
| Patients with pathological myopia with CNV |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Optical coherence tomography angiography | Device | Optical coherence tomography (OCT) is a noninvasive imaging method that uses reflected light to create pictures of the back of your eye |
| Measure | Description | Time Frame |
|---|---|---|
| choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia | choroidal neo-vascular membrane identified by Optical Coherence Tomography Angiography | through study completion, an average of 1 year |
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Inclusion Criteria:
Patients with pathological myopia where axial length more than 26 mm or refractive power more than -6 diopter with CNV in OCT with clear media and OCT-angio can be used.
Exclusion Criteria:
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Cnv in age related macular degeneration and in pathological myopia
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Arwa El-shabrakhity | Contact | 0111 462 4205 | arwa_mohamed@med.sohag.edu.eg |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8764797 | Background | Hee MR, Baumal CR, Puliafito CA, Duker JS, Reichel E, Wilkins JR, Coker JG, Schuman JS, Swanson EA, Fujimoto JG. Optical coherence tomography of age-related macular degeneration and choroidal neovascularization. Ophthalmology. 1996 Aug;103(8):1260-70. doi: 10.1016/s0161-6420(96)30512-5. | |
| 9457451 | Background | Secretan M, Kuhn D, Soubrane G, Coscas G. Long-term visual outcome of choroidal neovascularization in pathologic myopia: natural history and laser treatment. Eur J Ophthalmol. 1997 Oct-Dec;7(4):307-16. doi: 10.1177/112067219700700401. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | May 12, 2025 | |
| Reset | May 30, 2025 |
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| 16699445 | Background | Miller DG, Singerman LJ. Vision loss in younger patients: a review of choroidal neovascularization. Optom Vis Sci. 2006 May;83(5):316-25. doi: 10.1097/01.opx.0000216019.88256.eb. |
| 22523653 | Background | Kovach JL, Schwartz SG, Flynn HW Jr, Scott IU. Anti-VEGF Treatment Strategies for Wet AMD. J Ophthalmol. 2012;2012:786870. doi: 10.1155/2012/786870. Epub 2012 Feb 28. |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| May 12, 2025 | May 30, 2025 |