The Ekso GT ™ exoskeleton (Ekso Bionics, Inc. Richmond, CA, USA) used in the rehabilitation program has been approved by the Food and Drug Administration (FDA). Before starting the training session, each subject will undergo a thorough diagnosis to individually adjust the bionic skeleton. After entering the patient's data into the device's software, the physiotherapist selects the optimal training parameters. As the patient progresses during the training unit, the therapist will update the exoskeleton settings on an ongoing basis, so that the training is best suited to the current capabilities of the subject. Therapy with the use of the exoskeleton device will be carried out 4 times a week for 50 minutes a day. Additionally, individual physiotherapy (50 minutes) and upright standing (50 minutes) will be conducted 5 times a week.

The RoboGait stationary robot (Bama technologist, Turkey) will be used in the rehabilitation program. Before starting the training session, each subject will undergo detailed diagnostics in order to individually adjust the orthoses. The next step will be to put on a vest and inguinal straps on a wheelchair or standing, and then lift it up with the device, then attach it to the Robogait orthoses. After entering the patient's data into the software of the device, the physiotherapist selects the optimal training parameters. During the session, biofeedback is also displayed informing the patient and the therapist about the patient's activity level in the transfer phase and the support during walking for both lower limbs. Therapy with the use of the RoboGait device will be carried out 4 times a week for 50 minutes a day. Additionally, individual physiotherapy (50 minutes) and upright standing (50 minutes) will be conducted 5 times a week.

The Zebris FDM-T treadmill will be used in the rehabilitation program for gait analysis. Before each session, patients will be equipped with a harness for safety reasons. The need for a handrail will be assessed prior to each session and patients will be encouraged to support their hands as little as possible. Before starting the training session, each subject will undergo a thorough diagnosis in order to individually adjust the training parameters. Therapy with the use of the Zebris FDM-T treadmill will be carried out 4 times a week for 50 minutes a day. Additionally, individual physiotherapy (50 minutes) and upright standing (50 minutes) will be conducted 5 times a week.

The Pablo (Tyromotion) device will be used in the rehabilitation program. Before the start of the training session, each subject will undergo detailed diagnostics assessing the range of mobility in the shoulder, radiocarpal (frontal and sagittal plane), elbow (sagittal plane), and explosive strength of the cylindrical, pinch and lateral and three-point grip. The Force Control Index will also be designated. The next stage will be training on the Pablo device using visual and auditory biofeedback. The physiotherapist selects the optimal training parameters (type of pad, type of game, level of the game). Each training session will be stored in the software and recorded in the patient's medical records. Therapy with the use of the Pablo device will be carried out 4 times a week for 50 minutes a day. Additionally, individual physiotherapy (50 minutes) and upright standing (50 minutes) will be conducted 5 times a week.

In control Group the rehabilitation program will be carried out for a period of 4 weeks. In each of the studied groups, the rehabilitation program will include conventional physiotherapy sessions performed 5 times a week, consisting of 50 minutes a day of individual physiotherapy and 50 minutes a day of standing upright.

Fugl-Meyer Motor Assessment Scale for Upper Extremity is a comprehensive tool enabling measurement of motor function; it comprises 33 motor tasks, designed to assess general movements, precision movements, grip, coordination and speed. It is also possible to perform H subgroup tests - assessing superficial and deep sensibility, and J subgroup tests - for range of passive motion and pain induced by such movements. Individual tasks are assessed on a scale 0-2 0 - impossible task. The higher the score, the better.

The balance will be conducted using the Alfa platform. The board platform will be set up in parallel, 2 m from the walls of the room, where a tag will be placed to focus vision with open eyes during the trials. The measuring device will be calibrated before each test. The study will consist of two 30-s trials performed with open and closed eyes. The participant will be asked to conduct the test without shoes, in a relaxed standing position, with arms down by the sides.

Assessment of the strength of a cylindrical grip and extension as well as grips: pincer, lateral, two-point, three-point measured in kilograms and the force control index (0-100 points). The force control index is determined on the basis of: force reaction time, release time, force value exceeding, bending and extension time control.

The Zebris FDM-T is fitted with an electronic mat of 10,240 miniature force sensors, each approximately 0.85 × 0.85 cm embedded underneath the belt. The treadmill's contact surface measures 150 × 50 cm and its speed can be adjusted from 0.2 to 22 km/h, at intervals of 0.1 km/h. When the subject will stands/walks on the treadmill, the force will be exerted by his feet (the so-called reactive-normal force) and recorded by the sensors at a sampling rate of 120 Hz. Dedicated software will be integrated the force signals and provides 2D/3D graphic representation of major spatiotemporal parameters.

Based on the gait analysis carried out with the RoboGait, the isometric muscle strength will be obtained.

The EksoGT powered robotic exoskeleton will be used to provide the experimental intervention for this study. The number of steps during training will be assessed.

The test uses a wooden box, divided into two equal parts by a partition, as well as 150 blocks. The subject moves as many blocks as possible from one part of the box to the other during 60 seconds

The scale consists of 7 tasks (pass/fail grading); the patient is awarded 1 point for each activity performed successfully, or 0 points for a failure to perform. The maximum score of seven points may be achieved for the performance of the tasks. Higher score corresponds to better manual skills. The scale measures the proximal control of the upper limb and the manual skills

Barthel Index is a scale for ADL (Activities of Daily Living) measurement, with lower scores indicating greater dependency in ADL. The score value ranges between 0 and 100 points. The assessment of the total score is as follows: 0-20 completely dependent; 21-61 almost completely dependent; 62-85 dependent; 91-100 - independent

The TANITA is an 8-contact electrode system capable of acquiring segmental body composition analysis without the need for gel electrodes. Measurements using the TAN segmental body composition analyzer were recorded following a standardized 10-min standing period to minimize acute shifts in fluid distribution. Subject details were entered into the TAN, including information on clothing weight, gender, age, and height. When prompted, subjects stepped onto the footpads and grasped the handles. Analysis took approximately 10 sec during which time the subjects remained still and relaxed. Measurements were recorded in the standard mode.

The WHOQOL-Bref questionnaire was used to assess the quality of life, which allows to obtain a profile of quality of life on the basis of the analysis of the last 14 days in four domains: physical, psychological, social and environmental. Answers to the questions asked are classified in a five-point scale, and the interpretation of the obtained results has a positive direction. This means that the greater the number of points scored in each of the assessed domains, the better the quality of life of the subject.

The questionnaire enables the assessment of the functioning of people in the last 30 days in six domains of life: understanding and communicating, getting around, self-care, getting along with people, life activities and participation in society. Answers to the questions were classified in a five-point scale in which, along with the increase in the score obtained, the severity of the problem increases (no problem - 1 point, extremely big problem - 5 points). After summing up the results obtained in each of six domains and converting them to the 0-100 point range, it is also possible to assess the overall disability level, in which 0 points means no disability and 100 points - total disability

Lung Capacity was measured based on peak expiratory flow (PEF) and forced expiratory volume in 1 second (FEV1) using Peak flow meter (Peak Flow Meter Microlife PF 100, measuring range: 50-900 l/min and FEV1 0,01-9,99 l). Participants take a deep breath and blow air into the meter as fast as they can. For PEF and FEV1, at least three measurements were performed until the best values was selected

The 10 Meter Walk Test is a performance measure used to assess walking speed in meters per second over a short distance.

The questionnaire comprises seven questions for anxiety and seven questions for depression, and takes 2-5min to complete. Although the anxiety and depression questions are interspersed within the questionnaire, it is vital that these are scored separately. Cut-off scores are available for quantification, for both scales, scores of less than 7 indicate non-cases.