This is a prospective randomised study of the evaluation of the clinical IVF results after invasive PGT-A embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.

A randomized prospective study focusing on subfertile women undergoing IVF treatment followed by embryo transfer on the blastocyst stage.

Women assigned to group A proceed to embryo transfer, after invasive PGT-A embryo selection, while women of group B after non-invasive PGT-A assisted embryo selection.

IVF outcomes, regarding the success rate of the trasnfer and the time required to achieve conception is studied in both groups.

Inclusion Criteria:

• Women who followed IVF treatment
• 40 years old or older
• Single embryo transfer
• blastocyst stage cultured embryos

Exclusion Criteria:

• women under the age of 40 years
• not blastocyst transfer (transfers performed at earlier embryo stage)
• double embryotransfer
• women who had embryotransfer according to morphological criteria women whose embryos were not time-lapse monitored

Women 40 years old or older who were divided in two groups according to the embryo selection criteria for embryotransfer: women in group A proceeded to embryo transfer after invasive PGT-A assisted embryo selection and women in group B proceeded to embryo transfer after non- invasive PGT-A assisted embryo selection.