Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia

Analysis of Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia

The purpose of this study is to assess the safety and efficacy of ropivacaine and hydrocodone for nail-procedure associated pain management. The investigators hypothesize that ropivacaine with hydrocodone will be superior to ropivacaine with acetaminophen and ibuprofen for managing pain.

Inclusion Criteria:

• Patients undergoing fingernail or toenail, excision, or shave biopsy
• Must understand and voluntarily sign an informed consent form
• Must be male or female and aged 18-95 years at time of consent
• Must be able to adhere to the study visit schedule and other protocol requirements

Exclusion Criteria:

• Subject is unable to provide written informed consent for any reason
• Subject has peripheral vascular disease, arterial insufficiency, peripheral neuropathy
• Subject is on Aspirin, NSAIDs, or consumes a chronic medication for control of any other chronic pain
• Subject has a history of opioid or alcohol use disorder
• Subject has a history of peptic ulcer disease, gastritis, chronic renal insufficiency or a history of kidney disease, or has underlying liver disease
• Subject has a history of severe constipation
• Subject is sensitive or allergic to any of the elements included in this study
• Subject is unable to complete the required pain dairy
• Subject is pregnant, planning pregnancy, or nursing